L. Goldermann

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Peak levels of carbon tetrachloride (CCl4) as determined by head-space gas chromatography were observed 3-6 h following an acute oral dose of CCl4 in the blood, liver and fat of rats. Subsequently, there was a rapid decline of CCl4 levels. Conversely, serum activities of enzymes originating from the liver such as glutamate oxalacetate transaminase (GOT),(More)
A head-space gas chromatographic method for the determination of carbon tetrachloride in human blood is described. Standard samples with 0.5 ml whole blood containing different concentrations of CCl4 were analyzed at column temperatures ranging from 50° to 90°C. Advantages of this method include high sensitivity, simplicity in handling, rapid achievement of(More)
To study under standardized experimental conditions the effect of a CO2-induced hyperventilation therapy on carbon tetrachloride (CCl4) levels following acute CCl4 poisoning, rats received 2.5 ml CCl4/kg BW by gastric intubation and were subsequently either treated by CO2-induced hyperventilation or kept in an atmosphere containing air. Peak levels of CCl4(More)
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