L Gemmellaro

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Mother-to-child transmission of hepatitis C virus can take place in utero, during labour or after birth. Rate of vertical transmission varies widely between surveys but is around 5-6%. Maternal risk factors which may condition perinatal transmission risk are HIV/HCV coinfection, drug use, viral load, viral genotype, type of delivery and breastfeeding. On(More)
Changes in gastrointestinal (GI) bacteria caused by diet, antibiotics or other factors could alter enteric and systemic immune functions; changing the gut microflora composition by diet supplementation with specific live microbiota (probiotics) may be beneficial. The 'natural' target of ingested probiotics is the intestine, its microflora and associated(More)
Background: Lactoferrin (LF) is a mammalian iron-binding glycoprotein with antiviral effects, possibly inhibiting HIV-1 replication. The aim of the present study is to evaluate the effect of bovine LF on immunological and virological status of HIV-1 vertically infected childrenMethods: Twenty-two HIV-vertically-infected children (9 girls, 13 boys; age 3–18(More)
In HIV infected children, CD45+CD4+ T lymph. reconstitution has been related to efficient thymopoiesis. Because human thymus undergoes spontaneous involution at a relatively young age, institution of antiretroviral therapy early in the course of infection has been recommended. 12 HIV vertically infected children aged 4-8 years were investigated T-cell(More)
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