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Journals and Conferences
Benzodioxane analogues of pseudobaptigenin with alkyl fragments in positions 2 and 6 of the chromone ring have been synthesized from α-(1,4-benzodioxan-6-yl)-2-hydroxy-6-alkylacetophenones.
Benzodioxepane analogues of pseudobaptigenin have been synthesized and their structures have been established by chemical transformations, elementary analysis, and PMR spectroscopsy.
The reactions of 1,3-benzodioxolane, 1,4-benzodioxane, and 1,5-benzodioxepane analogs of isoflavones with hydrazine derivatives have been studied. It has been found that under the action of hydrazines the new isoflavones recyclize into 3,4-diarylpyrazones. Their structures have been confirmed by their PMR spectra.
It is known [i] that furan analogs of flavones possess biological activity, with an effect on the living organism similar to that of khellin, a natural furochromone which shows strong antispasmodic action. In an earlier study of physiological activity, we prepared the furan analogs of isoflavones (I) [2, 3], and found that several of them showed heart… (More)
Flavonoids are a vast and unusual group of natural compounds interest in which has constantly attracted the attention of many investigators. Flavonoids display significant physiological activity and are nontoxic; consequently they are used widely for medicinal purposes. Highly effective drugs based on the natural flavonoids caused in their turn the growth… (More)