L Berlinger

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Background HIV-1 adsorption and entry into target cells is initiated by the binding of the viral envelope glycoprotein gp120 to cell surface molecules. While the central role of CD4 as entry receptor is undoubted, it has been debated for long whether the initial contact of the virus with the target cell occurs through interaction with CD4 itself or(More)
Background A considerable effort in the development of HIV vaccines has been directed towards eliciting neutralizing antibody responses that match the activities of the membrane-proximal external region (MPER) specific monoclonal antibodies 2F5 and 4E10. Recent years have broadened our knowledge in the structural composition of the MPER region, its(More)
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