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We performed a double-blind study in 101 preterm infants who weighed less than or equal to 1500 g at birth, who had respiratory distress, and who survived for at least four weeks, to evaluate the efficacy of oral vitamin E in preventing the development of retrolental fibroplasia. Weekly indirect ophthalmologic examinations begun when the infants were three(More)
To evaluate the efficacy of four early intramuscular injections of vitamin E given in addition to continuous minimal oral vitamin E supplementation, 168 very low-birth-weight infants (less than or equal to 1,500 g) have enrolled in a randomized, double-masked, clinical study. All infants received vitamin E orally, 100 mg/kg/d. In addition, on days 1, 2, 4,(More)
To further evaluate the efficacy of oral vitamin E in preventing the development of severe retrolental fibroplasia (RLF) in very low-birth-weight infants, 100 infants treated with 100 mg/kg/d of vitamin E (dl-alpha-tocopheryl acetate) were compared with 75 infants treated with 5 mg/kg/d of vitamin E (dl-alpha-tocopherol) in the same nursery during the(More)
OBJECTIVE To determine the efficacy and safety of topical 0.3% ciprofloxacin hydrochloride ophthalmic ointment in the treatment of bacterial keratitis. DESIGN Prospective case series with a nonrandomized comparison of culture-positive, evaluable cases (ciprofloxacin ointment group) with culture-positive, concurrent patients (nonenrolled group) treated(More)
Central corneal thickness changes were monitored in nine subjects who wore low water content hydrogel lenses of varying thickness for 3 h in the open and closed eye conditions. At the end of 3 h of lens wear, corneal deswelling to prelens thickness for the different levels of hypoxia was determined by pachometry performed every 5 min for the first 30 min,(More)
The zone of zero-associated phoria (ZZAP) was determined for patients with convergence insufficiency. The ZZAP for these patients differs from that of asymptomatic patients. It is concluded that the ZZAP may be used as a supplemental test to help the clinician detect convergence insufficiency and possibly other binocular deficiencies.
The vessel deviation to disc ratio (VDR) of the optic nerve head can be defined for a given meridian as the ratio of the size of the cup as indicated by small blood vessel deviation in that meridian to the size of the disc. Thus, VDR is a relative measure similar to cup/disc ratio. The difference between VDR and other methods of measuring cup/disc ratio is(More)