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To evaluate the efficacy of four early intramuscular injections of vitamin E given in addition to continuous minimal oral vitamin E supplementation, 168 very low-birth-weight infants (less than or equal to 1,500 g) have enrolled in a randomized, double-masked, clinical study. All infants received vitamin E orally, 100 mg/kg/d. In addition, on days 1, 2, 4,(More)
We performed a double-blind study in 101 preterm infants who weighed less than or equal to 1500 g at birth, who had respiratory distress, and who survived for at least four weeks, to evaluate the efficacy of oral vitamin E in preventing the development of retrolental fibroplasia. Weekly indirect ophthalmologic examinations begun when the infants were three(More)
To further evaluate the efficacy of oral vitamin E in preventing the development of severe retrolental fibroplasia (RLF) in very low-birth-weight infants, 100 infants treated with 100 mg/kg/d of vitamin E (dl-alpha-tocopheryl acetate) were compared with 75 infants treated with 5 mg/kg/d of vitamin E (dl-alpha-tocopherol) in the same nursery during the(More)
OBJECTIVE To determine the efficacy and safety of topical 0.3% ciprofloxacin hydrochloride ophthalmic ointment in the treatment of bacterial keratitis. DESIGN Prospective case series with a nonrandomized comparison of culture-positive, evaluable cases (ciprofloxacin ointment group) with culture-positive, concurrent patients (nonenrolled group) treated(More)
Central corneal thickness changes were monitored in nine subjects who wore low water content hydrogel lenses of varying thickness for 3 h in the open and closed eye conditions. At the end of 3 h of lens wear, corneal deswelling to prelens thickness for the different levels of hypoxia was determined by pachometry performed every 5 min for the first 30 min,(More)
Evaluation of the fluorescein pattern is the main clinical indicator of the fit of a rigid gas permeable (RGP) contact lens to the cornea. Traditionally, manufacturers inventory RGP lenses in 0.05-mm base curve increments. The objective of this study was to test the hypothesis that experienced practitioners are not able to discern base curve/cornea(More)
For paraxial objects viewed at finite distances from the correction plane, retinal image size and retinal distortions due to astigmatism are obtained for spectacle- or contact-lens-corrected aphakic individuals with astigmatism. Our methods are based not on the analysis of schematic or reduced eyes but on clinical measurements (corneal, refractive,(More)
A simple clinical predictor of the amount of spectacle convex lens power that will be needed to correct the refractive error of an aphakic patient after cataract surgery is developed based on clinical measures of anterior corneal surface power (keratometer measurements) and axial length. This predictor derived from matrix optics is compared to previous ones(More)