• Publications
  • Influence
Evaluation of Wistar rats' individual sensitivity to the development of physical dependence on morphine.
Behavioral and physiological indices which could be symptoms of individual Wistar rats' sensitivity to the development of physical dependence on morphine, were studied. This state was induced inExpand
  • 19
Differences in morphine reinforcement property in two inbred rat strains: associations with cortical receptors, behavioral activity, analgesia and the cataleptic effects of morphine
The purpose of the current study was to investigate genetic differences between two inbred strains of rats, Fisher-344 (F344/N) and Wistar Albino Glaxo (WAG/GSto), in a number of drug-naive andExpand
  • 21
[The pharmacological properties of karazedin].
The original agent 1,2,3,4,5,5a,6,10b-octahydroazepino-[4,5-b]indole (carazedine), an analog of the highly active antipsychotic drug carbidine, was synthesized. This agent was found to have variousExpand
  • 1
[Neurotropin suppression of the manifestations of the naloxone-provoked withdrawal syndrome in morphine-dependent rats].
Neurotropin was developed by Nippon Zoki Pharmaceutical Co. Ltd. It is produced by inoculating vaccine virus into rabbits and the effective substances are extracted from neuro-immuno inflamedExpand
[The role of visual stimuli in the acquisition of place preference with morphine reinforcement].
In experiments with rats was studied the role of visual stimuli in conditioning of place preference in a T-shaped chamber, certain stimuli being combined with morphine injection (5 mg/kg). IntensityExpand
[An assessment of the individual sensitivity of Wistar rats to the development of morphine dependence].
A search was made for behavioral and physiological indicators which could serve predictors of the individual sensitivity of Wistar rats to the development of physical morphine dependence. AnimalsExpand
[Method for evaluating the reinforcing properties of morphine in a model of addictive behavior].
An animal model of addiction is described. The albino rats learned to come into the right arm of the Y-type maze where they received intraperitoneal injections of morphine in a dose of 5 mg/kg orExpand