L A Kotova

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AIM To assess a hypolipidemic effect and tolerance of phenofibrate (lipantil 200M) in different variants of treatment in patients with combined hyperlipidemia having moderate and high levels of triglycerides (TG). MATERIAL AND METHODS A total of 26 patients (16 males, 10 females; age 32-67, mean age 55.1 years) received lipantil 200M (phenofibrate) in a(More)
AIM To analyze retrospectively data on lipid lowering efficacy, tolerability and safety of different doses of simvastatin in patients with primary hyperlipidemia. MATERIAL AND METHODS Thirty five patients (mean age 54.9-/+8.5 years, 15 men, 20 women) received simvastatin for 3-6 months in doses 10 (n=12), 20 (n=8), 40 (n=10) and 80 (n=5) mg/day. Average(More)
AIM To assess orthogonal ECG system McFee-Parungao in exercise test performed by patients with ischemic heart disease (IHD). MATERIAL AND METHODS The trial included 103 patients: 41 patients with IHD, 23 patients with IHD combined with arterial hypertension and 39 control patients free of IHD. All the patients performed bicycle exercise with ECG(More)
The general and acid-stable activities, i.e. anti-tryptic activity (ATA) and anti-chemotryptic activity (ACTA), of a trypsin inhibiter in the urine (TIU) were determined for patients and donors. A lack of reliable differences between the general and acid-stable activities in donors and in patients with nephritis is indicative of that TIU is the main(More)
To determine the HLA-B27 gene subtypes associated with joint diseases we examined 55 patients (35 with ankylosing spondylarthritis (AS), 13 with rheumatoid arthritis (RA), 5 with Reiter's syndrome, 2 with psoriatic arthritis). DNA amplification combined with sequence specific oligonucleotide hybridization were used to identify six HLA-B27 gene alleles. In(More)
Out of 12 patients with primary hyperlipidemia (HL) included in the study ischemic heart disease was diagnosed in 4 and hypertension stage I-II in 6 patients. HL stage II B, III, IV and V was registered in 7, 2, 2 and 1 patients, respectively. Hypolipidemic therapy included hypolipidemic diet and Lipanor (Sanofi-Chinoin-Winthrop, France) in a dose 100 mg(More)
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