L A Giroldi

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Sir, We read with great interest the paper by Bao et al (2014) entitled 'COUP-TFII regulates metastasis of colorectal adenocarcinoma cells by modulating Snail1', showing upregulation of Snail and down-regulation of E-cadherin in the human epithelial intestinal cell line HIEC overexpressing COUP-TFII upon transfection (Bao et al, 2014; Figure 5) and converse(More)
E-cadherin is a ('a-*-dependent cell adhesion molecule which plays an important role in normal growth and development via mediation of homotypic, homophilic cell-cell interaction. Recent studies suggest that E-cadherin may be important in neoplastic progression as well, partic ularly as a suppressor of invasion. We have previously demonstrated that the(More)
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