Lívia A. Carvalho

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The glucocorticoid receptor: Pivot of depression and of antidepressant treatment?

Christoph Anacker, Patricia Ana Zunszain, Lívia A. Carvalho, Carmine M Pariante
Psychoneuroendocrinology
2011

Hyperactivity of the hypothalamus-pituitary-adrenal (HPA) axis and increased levels of glucocorticoid hormones in patients with depression have mostly been ascribed to impaired feedback regulation of… (More)

Glucocorticoids, cytokines and brain abnormalities in depression

Patricia Ana Zunszain, Christoph Anacker, Annamaria Cattaneo, Lívia A. Carvalho, Carmine M Pariante
Progress in Neuro-Psychopharmacology and…
2011

Major depression (MD) is a common psychiatric disorder with a complex and multifactor aetiology. Potential mechanisms associated with the pathogenesis of this disorder include monoamine deficits,… (More)

Lack of clinical therapeutic benefit of antidepressants is associated overall activation of the inflammatory system.

Lívia A. Carvalho, John Paul De La Torre, +5 authors Carmine M Pariante
Journal of affective disorders
2013

Despite the evidence of an association between depression and increased inflammatory markers, still little is known in relation to the most severe cases of the disorder i.e., those who fail to… (More)

Executive dysfunction in euthymic bipolar disorder patients and its association with plasma biomarkers.

Izabela Guimarães Barbosa, Natália Pessoa Rocha, +5 authors Antônio Lúcio Teixeira
Journal of affective disorders
2012

BACKGROUND Despite the old Kraepelinean concept that bipolar disorder (BD) does not evolve with cognitive decline, the presence of cognitive impairment, especially executive dysfunction has been… (More)

Clomipramine In Vitro Reduces Glucocorticoid Receptor Function in Healthy Subjects but not in Patients with Major Depression

Lívia A. Carvalho, Mario Francisco P. Juruena, +4 authors Carmine M Pariante
Neuropsychopharmacology
2008

Previously, we have shown that in vitro antidepressants modulate glucocorticoid receptor (GR) function and expression, and have suggested that these effects could be relevant for the mechanism of… (More)

Joanna Rybka, Daria Kupczyk, +7 authors Józef Kędziora
Cardiovascular Toxicology
2010

The purpose of this study was to analyze glutathione antioxidant defense system in elderly patients treated for hypertension. Studies were carried out in the blood collected from 18 hypertensive and… (More)

Neuroimmune endocrine effects of antidepressants

Marco Antonioli, Joanna Rybka, Lívia A. Carvalho
Neuropsychiatric disease and treatment
2012

Antidepressant pharmacotherapy is to date the most often used treatment for depression, but the exact mechanism of action underlying its therapeutic effect is still unclear. Many theories have been… (More)

In vitro modulation of the glucocorticoid receptor by antidepressants.

Clinical studies have demonstrated an impairment of glucocorticoid receptor (GR)-mediated negative feedback on the hypothalamus-pituitary-adrenal (HPA) axis in patients with major depression (GR… (More)

Clinical characteristics of inflammation-associated depression: Monocyte gene expression is age-related in major depressive disorder

Laura Grosse, Lívia A. Carvalho, Annemarie J. M. Wijkhuijs, Silja Bellingrath, Volker Arolt
Brain, Behavior, and Immunity
2015

Increased inflammatory activation might only be present in a subgroup of depressed individuals in which immune processes are especially relevant to disease development. We aimed to analyze… (More)

Singing modulates mood, stress, cortisol, cytokine and neuropeptide activity in cancer patients and carers

Daisy Fancourt, Aaron Williamon, Lívia A. Carvalho, Andrew Steptoe, Rosie Dow, Ian Lewis
Ecancermedicalscience
2016

There is growing evidence that psychosocial interventions can have psychological benefits for people affected by cancer, including improved symptoms of mental health and wellbeing and optimised… (More)

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