László Hegedüs

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BACKGROUND Phthalates are widely used chemicals, and human exposure is extensive. Recent studies have indicated that phthalates may have thyroid-disrupting properties. OBJECTIVE We aimed to assess concentrations of phthalate metabolites in urine samples from Danish children and to investigate the associations with thyroid function, insulin-like growth(More)
We consider stateless counter machines which mix the features of one-head counter machines and a special type of two-head Watson-Crick automata (WK-automata). Our biologically motivated machines have heads that read the input starting from the two extremes. The reading process is finished when there are no more symbols between the heads. Depending on(More)
Thyroid function was investigated in 100 manic-depressive patients. Goiter was more common in patients treated with lithium for 1-5 years (44%) or more than 10 years (50%) than in patients who never received lithium (16%). Smoking contributed significantly to thyroid size and goiter. In nonsmoking patients, ultrasonically determined thyroid volume was(More)
BACKGROUND Hyperthyroidism has been linked with different morbidities, like atrial fibrillation, stroke and diabetes mellitus. However, our knowledge regarding the extent and temporal relation between hyperthyroidism and other diseases is fragmented. Here, we aimed at evaluating various morbidities before and after the diagnosis of hyperthyroidism. (More)
BACKGROUND Hypothyroidism has been linked with an increased risk of other morbidities, such as cardiovascular diseases and diabetes mellitus. However, the temporal relationship between these diseases and the diagnosis of hypothyroidism is not well illuminated. Such information may provide insight into causal relationships between hypothyroidism and other(More)
BACKGROUND Patients with chronic autoimmune thyroiditis have impaired health-related quality of life. The thyroid gland has a high selenium concentration, and specific selenoprotein enzyme families are crucial to immune function, and catalyze thyroid hormone metabolism and redox processes in thyroid cells. Previous randomized controlled trials have found(More)
CONTEXT Little is known about how thyroid diseases affect work ability. OBJECTIVE The objective of this study was to evaluate the risk of work disability for patients with thyroid disease compared with the general population. DESIGN, SETTING, AND PARTICIPANTS In a longitudinal register study, outpatients (n = 862) with nontoxic goiter, hyperthyroidism,(More)
BACKGROUND Hypothyroidism is often diagnosed, and subsequently treated, due to health-related quality of life (HRQL) issues. However, HRQL following treatment has never previously been assessed in longitudinal descriptive studies using validated instruments. OBJECTIVE To investigate disease-specific (ThyPRO) and generic (SF-36) HRQL, following(More)
—The model we consider are stateless counter machines which mix the features of one-head counter machines and special two-head Watson-Crick automata (WK-automata). These biologically motivated machines have reading heads that read the input starting from the two extremes. The reading process is finished when the heads meet. The machine is realtime or(More)