Kyung Jin Lee

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hHR23B is the human homologue of the yeast protein RAD23 and is known to participate in DNA repair by stabilizing xeroderma pigmentosum group C protein. However, hHR23B and RAD23 also have many important functions related to general proteolysis. hHR23B consists of N-terminal ubiquitin-like (UbL), ubiquitin association 1 (UBA1), xeroderma pigmentosum group C(More)
Schizophrenia and obsessive-compulsive disorder (OCD) are assumed to be neurodevelopmental disorders. To examine the cortical patterns in the two disorders, three-dimensional fractal dimension (FD) of skeletonized cerebral cortical surface was estimated from magnetic resonance (MR) images of 50 patients with schizophrenia, 45 patients with OCD and 26(More)
Satoru Emori,1 Eduardo Martinez,2 Kyung-Jin Lee,3,4 Hyun-Woo Lee,5 Uwe Bauer,1 Sung-Min Ahn,1 Parnika Agrawal,1 David C. Bono,1 and Geoffrey S. D. Beach1,* 1Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA 2Departmento Fı́sica Aplicada, Universidad de Salamanca, Plaza de los Caidos(More)
The hepatoprotective effects of kahweol and cafestol, coffee-specific diterpenes, on the carbon tetrachloride (CCl(4))-induced liver damage as well as the possible mechanisms involved in these protections were investigated. Pretreatment with kahweol and cafestol prior to the administration of CCl(4) significantly prevented the increase in the serum levels(More)
This study was designed to investigate the protective effects of the phenethyl ester of caffeic acid (CAPE) against carbon tetrachoride (CCl(4))-induced hepatotoxicities in mice. Pretreatment with CAPE prior to administration of CCl(4) significantly prevented the increases in serum alanine, aspartate aminotransferase and alkaline phosphatase activities,(More)
This study describes actinobacteria isolated from the marine sponge Haliclona sp. collected in shallow water of the South China Sea. A total of 54 actinobacteria were isolated using media selective for actinobacteria. Species diversity and natural product diversity of isolates from marine sponge Haliclona sp. were analysed. Twenty-four isolates were(More)
The authors evaluated the trait/state issues of harm avoidance in depressive-spectrum disorders and its predictive potential for antidepressant response. Subjects with Diagnostic and Statistical Manual of Mental Disorders (4th edn; DSM-IV) major depressive disorder (n = 39), dysthymic disorder (n = 37), depressive personality disorder (n = 39), and healthy(More)
Regulation of progesterone receptor (PR) by estradiol-17beta (E(2)) in mouse uterine and vaginal epithelia was studied. In ovariectomized mice, PR expression was low in both vaginal stroma and epithelium, but high in uterine epithelium. E(2) induced PR in vaginal epithelium and stroma, but down-regulated PR in uterine epithelium. Analysis of estrogen(More)
STUDY OBJECTIVE To evaluate the feasibility of a single-port laparoscopic salpingectomy in the surgical treatment of tubal pregnancy. DESIGN Prospective cohort study (Canadian Task Force classification II-2). SETTING University teaching hospital PATIENTS Twenty women with tubal pregnancy, as determined by ultrasonography. INTERVENTION All patients(More)
The possibility of exciting microwave oscillations in a nanomagnet by a spin-polarized current, as predicted by Slonczewski and Berger, has recently been demonstrated. This observation opens important prospects of applications in radiofrequency components. However, some unresolved inconsistencies are found when interpreting the magnetization dynamics within(More)