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The Separate and Combined Effects of Insulin, Dexamethasone andGrowth Hormone on the OB Gene Expression and Leptin Secretionfrom Cultured Human Visceral Adipose Tissue
The mechanism suggested is that insulin may increase leptin secretion in cytoplasm only after dexamethasone increases the expression of OB gene, which is necessary to elucidate the mechanism of the action of insulin on leptin secretion after increasing OB gene expression by dexamETHasone.