Kyoung-hye Yoon

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PURPOSE The beaded filament is a cytoskeletal structure that has been found only in the lens fiber cell. It includes phakosin and filensin, two divergent members of the intermediate filament family of proteins that are also unique to the fiber cell. The authors sought to determine what function the beaded filament fulfills in the lens. METHODS Light(More)
The mammalian olfactory system detects a plethora of environmental chemicals that are perceived as odors or stimulate instinctive behaviors. Studies using odorant receptor (OR) genes have provided insight into the molecular and organizational strategies underlying olfaction in mice. One important unanswered question, however, is whether these strategies are(More)
The olfactory system translates a vast array of volatile chemicals into diverse odor perceptions and innate behaviors. Odor detection in the mouse nose is mediated by 1,000 different odorant receptors (ORs) and 14 trace amine-associated receptors (TAARs). ORs are used in a combinatorial manner to encode the unique identities of myriad odorants. However,(More)
As space flight become more accessible in the future, humans will be exposed to gravity conditions other than our 1G environment on Earth. Changes in physiology and anatomy in altered gravity conditions have long been observed, especially the loss of muscle mass during long-term space habitation, the reason for which is not fully understood. Although much(More)
The mechanisms by which odors induce instinctive behaviors are largely unknown. Odor detection in the mouse nose is mediated by >1, 000 different odorant receptors (ORs) and trace amine-associated receptors (TAARs). Odor perceptions are encoded combinatorially by ORs and can be altered by slight changes in the combination of activated receptors. However,(More)
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