Kyoko Shimotsu

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Aralar is a mitochondrial calcium-regulated aspartate-glutamate carrier mainly distributed in brain and skeletal muscle, involved in the transport of aspartate from mitochondria to cytosol, and in the transfer of cytosolic reducing equivalents into mitochondria as a member of the malate-aspartate NADH shuttle. In the present study, we describe the(More)
The simple photoreceptors Ip-1 and Ip-2 are intrinsically light-sensitive neurons that exist in the abdominal ganglion of the sea slug Onchidium verruculatum. Using isolated ganglia and semi-intact or intact animal preparations, the present studies examined the light-sensing and physiological roles of Ip-1 and Ip-2 cells, which respond jointly to light by(More)
Aralar, an isoform of the calcium-binding aspartate-glutamate mitochondrial carrier, is distributed specifically in the brain and skeletal muscles. The aim of the present study was to investigate behaviors induced by the decreased expression of aralar in the brain and to assess whether expression of brain tryptophan hydroxylase, a key enzyme in serotonin(More)
Aralar, an isoform of the calcium-binding aspartate-glutamate mitochondrial carrier, is distributed specifically in the brain and skeletal muscles. The aim of the present study was to investigate behaviors induced by the decreased expression of aralar in the brain and to assess whether expression of brain tryptophan hydroxylase, a key enzyme in serotonin(More)
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