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Farnesylpyridinium, an analog of isoprenoid farnesol, induces apoptosis but suppresses apoptotic body formation in human promyelocytic leukemia cells
Involvement of oxidative stress induction in Na+ toxicity and its relation to the inhibition of a Ca2+ -dependent but calcineurin-independent mechanism in Saccharomyces cerevisiae.
- Toshio Tanaka, Kyoichi Nishio, Y. Usuki, Ken-Ichi Fujita
- Biology, ChemistryJournal of bioscience and bioengineering
UMPC16, but not CsA, accelerated mitochondrial reactive oxygen species (ROS) generation in combination with Na+, suggesting its inhibition of a Ca2+ -dependent but calcineurin-independent mechanism for protection against Na+ toxicity.
The enzyme composition
PROBLEM TO BE SOLVED: To provide an enzyme composition for decreasing glucose in the stomach and/or the intestines and reducing calorie uptake by its intake and utilization of enzyme reaction and for…
Enzyme engineering of fungal-derived FAD-GDH by circular permutation
This study employed a technique called circular permutation (CP) to explore the effects on enzyme substrate specificity of FAD-GDH for glucose by connecting the native protein termini via a covalent soft linker and introducing new ends through the cleavage of an existing peptide bond.