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Farnesylpyridinium, an analog of isoprenoid farnesol, induces apoptosis but suppresses apoptotic body formation in human promyelocytic leukemia cells
FPy exhibited a cytochalasin‐like effect on spatial arrangement of actin filament independent of its apoptosis‐inducing activity, and could suppress the induction of apoptotic body formation in HL‐60 cells by typical inducers of apoptosis such as actinomycin D or anisomycin. Expand
Involvement of oxidative stress induction in Na+ toxicity and its relation to the inhibition of a Ca2+ -dependent but calcineurin-independent mechanism in Saccharomyces cerevisiae.
UMPC16, but not CsA, accelerated mitochondrial reactive oxygen species (ROS) generation in combination with Na+, suggesting its inhibition of a Ca2+ -dependent but calcineurin-independent mechanism for protection against Na+ toxicity. Expand
The enzyme composition
PROBLEM TO BE SOLVED: To provide an enzyme composition for decreasing glucose in the stomach and/or the intestines and reducing calorie uptake by its intake and utilization of enzyme reaction and forExpand
Enzyme engineering of fungal-derived FAD-GDH by circular permutation
Narrowing the substrate specificity of FAD-GDH for glucose is desired for future application. In this study, we employed a technique called circular permutation (CP) to explore the effects on enzymeExpand