Kyohei Hayashi

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The purpose of this study was to examine whether a high serum concentration of phytoestrogens reduces the risk of prostate cancer in a case-control study nested in a community-based cohort in Japan (Japan Collaborative Cohort (JACC) Study). Information on lifestyles and sera of the subjects were collected in 1988-90, and they were followed up to 1999.(More)
Shift workers have been reported to have an increased risk of some cancers. However, the risk of prostate cancer in shift workers is not known to have been examined previously. This study prospectively examined the association between shift work and risk of prostate cancer incidence among 14,052 working men in Japan enrolled in a large-scale prospective(More)
A seroepidemiologic, nested case-control studywas conducted to evaluate the risk for atrophicgastritis associated with Helicobacter pylori infection.Atrophic gastritis was diagnosed on the basis of serum pepsinogen levels: pepsinogen I level≤70 ng/ml and pepsinogen I/pepsinogen II ratio≤3.0. Cases were 23 men and 39 women who were notdiagnosed with atrophic(More)
BACKGROUND The incidence of kidney cancer is high in Western and Northern Europe and North America, and low in Asia. Although the incidence of kidney cancer in Japan is lower than the rates in the other industrialized countries, there is no doubt that it is increasing. METHODS We evaluated the risk factors for kidney cancer death using the database of the(More)
BACKGROUND Diabetes mellitus (DM) is reported as being a risk factor associated with kidney cancer in Western countries. The incidence of both kidney cancer and DM is lower in Japan than the other developed countries, albeit on the rise. METHODS We evaluated the risk factors for kidney cancer mortality using the database of the Japan Collaborative Cohort(More)
BACKGROUND The relationships between dietary habits and urothelial cancer have been discussed in many epidemiologic studies, however, they have not been sufficiently elucidated. In the present study, the associations of dietary habits with the risk of urothelial cancer incidence were evaluated taking into consideration sex, age, and smoking habits. (More)
Stroke patients who underwent computed tomography (CT) were enrolled in a stroke registry in Akita, Japan, which comprised 7288 first-ever stroke cases during 1999 to 2001. Differences in age and sex were evaluated with respect to type-specific incidences and lesion sites. The incidence increased with age, except for subarachnoid hemorrhage (SAH) in men(More)
Gastroesophageal reflux disease (GERD) is a common condition, and acid-suppressing agents are the mainstays of treatment. For the acute medical management of GERD, two different strategies can be proposed: either the most effective therapy, i.e., proton-pump inhibitors (PPIs), can be given first, or histamine H2-receptor antagonists (H2RAs) can be attempted(More)
Clinically nonfunctioning pituitary adenomas (NFAs) may be hormonally inactive tumors of differentiated cells, mainly not only gonadotroph adenomas (GAs) but also silent corticotroph adenomas (SCAs) and other differentiated silent adenomas. Recently, the use of transcription factors has been recommended to confirm cytodiffererentiation of these neoplasms.(More)
BACKGROUND We have been conducting a cohort study named "the Japan Collaborative Cohort Study (JACC Study) for Evaluation of Cancer Risk sponsored by the Ministry of Education, Science, Sports and Culture of Japan (Monbusho)" since 1988. The aim of this paper is to describe the mortality of our JACC cohort in the follow-up period from 1988 through 1999, to(More)