Kyle Koo-Il Seo

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BACKGROUND Adipose-derived stem cells (ASCs) are mesenchymal stem cells that have recently been applied to tissue repair and regeneration. Keratinocytes and dermal fibroblasts play key roles in cutaneous wound healing. OBJECTIVE We investigated the paracrine effects of ASCs on HaCaT cells (i.e., immortalized human keratinocytes) and human dermal(More)
BACKGROUND A paucity of reports exist on the use of botulinum toxin type A injections as an alternative noninvasive treatment for masseteric hypertrophy. OBJECTIVE To evaluate the effects of botulinum toxin type A on masseteric hypertrophy using computed tomography. METHODS Percutaneous intramuscular injections of botulinum toxin type A of 30 U per side(More)
BACKGROUND Botulinum neurotoxin type A (BoNT/A) has been used as an analgesic for myofascial pain syndromes, migraine, and other types of headaches. Although an antinociceptive effect of central or peripheral administration of BoNT/A is suggested, the effect at the spinal level is still unclear. In this study, we evaluated the antinociceptive effect of(More)
BACKGROUND There are no reports of objectively evaluating the efficacy of filler rhinoplasty by anthropometric techniques. OBJECTIVE To objectively demonstrate the effectiveness of filler rhinoplasty by anthropometric analysis. MATERIALS AND METHODS A total of 242 patients who revisited the clinic within 2 months of undergoing hyaluronic acid filler(More)
Alpha1a-adrenergic receptor (AR) primarily mediates the contraction of the prostatic and cavernous smooth muscles. Among clinically available alpha1-AR antagonists for the medical management of benign prostatic hyperplasia (BPH), tamsulosin has a modest selectivity for alpha1A- and alpha1D- over alpha1B-ARs. To compare the effects of various alpha1-AR(More)
BACKGROUND Foremost fine hairs in the frontal hairline region are critical in hair transplantation for hairline correction (HTHC) in women. However, there are few studies on a nonsurgical revisionary method for improving an unnatural foremost hairline with thick donor hairs resulting from a previous HTHC. OBJECTIVE To investigate the efficacy and safety(More)
INTRODUCTION Among non-ablative devices for wrinkle reduction and skin laxity, long pulsed 1064 nm Nd:YAG laser (LPND) has considerable effectiveness. It can penetrate to deep dermis due to its longer wavelength. This study assesses the efficacy and safety of LPND applying new parameters for skin rejuvenation in Korean subjects. METHODS A prospective(More)
Sympathetic neurolysis is very important in treating chronic pain, especially sympathetically maintained pain. However, conventional neurolytic agents destroy nerve fibers nonselectively and may leave serious complications. Botulinum toxin type A (BTA) selectively acts on cholinergic nerves and inhibits the secretion of acetylcholines (Ach) at the involved(More)
BACKGROUND The botulinum neurotoxin Type A (BTX) injection into the masseter muscle often causes a change in the facial expression. There is as yet no precise anatomic evidence to support this etiologic factor of constrained facial expressions. OBJECTIVE The aim of this study was to clarify the location and boundaries of the risorius muscle and its(More)
BACKGROUND The aging process is a complex interplay of intrinsic and extrinsic factors across multiple layers of the face. Accordingly, combining aesthetic interventions targeting different manifestations of aging often leads to better results than single modalities alone. However, no guidelines for a pan-facial approach using multiple interventions have(More)