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Cyclo(phenylalanine-proline) is produced by various organisms such as animals, plants, bacteria and fungi. It has diverse biological functions including anti-fungal activity, anti-bacterial activity and molecular signalling. However, a few studies have demonstrated the effect of cyclo(phenylalanine-proline) on the mammalian cellular processes, such as cell(More)
The inflammatory response contributes substantially to secondary injury cascades after spinal cord injury, with both neurotoxic and protective effects. However, epigenetic regulations of inflammatory genes following spinal cord injury have yet to be characterized thoroughly. In this study, we found that histone H3K27me3 demethylase Jmjd3 expression is(More)
One of the most challenging ongoing issues in the field of 3D visual research is how to interpret human 3D perception over virtual 3D space between the human eye and a 3D display. When a human being perceives a 3D structure, the brain classifies the scene into the binocular or monocular vision region depending on the availability of binocular depth(More)
One of the most challenging ongoing issues in the field of 3D visual research is how to perceptually quantify object and surface visualizations that are displayed within a virtual 3D space between a human eye and 3D display. To seek an effective method of quantification, it is necessary to measure various elements related to the perception of 3D objects at(More)
Histone H3K27me3 demethylase JMJD3 has been shown to be involved in keratinocyte differentiation and wound healing. However, the exact molecular mechanism underlying JMJD3-mediated keratinocyte wound healing has not been fully elucidated. In this study, we report on the biological function of JMJD3 in keratinocyte wound healing using in vitro cell and in(More)
Emerging multimedia applications have increased the need for video quality measurement. Motion is critical to this task, but is complicated owing to a variety of object movements and movement of the camera. Here, we categorize the various motion situations and deploy appropriate perceptual models to each category. We use these models to create a new(More)
PURPOSE We investigated the correlations between optical quality parameters obtained from the double-pass system and ocular aberrations obtained from the ray-tracing aberrometer in multifocal intraocular lens (IOL) implanted eyes. MATERIALS AND METHODS Twenty eyes from 20 patients were enrolled in this study. Modulation transfer function cutoff frequency,(More)
To compare optical quality, ocular scattering, and higher-order aberrations (HOAs) after laser in-situ keratomileusis (LASIK) versus laser epithelial keratomileusis (LASEK). A total of 47 eyes from 47 participants who had undergone LASIK (group I) or LASEK (group II) procedure at least 6 months prior were enrolled. Ocular aberrations and modulation transfer(More)
Mammalian SFMBTs have been considered to be polycomb group repressors. However, molecular mechanisms underlying mammalian SFMBTs-mediated gene regulation and their biological function have not been characterized. In the present study, we identified YY1 and methylated histones as interacting proteins of human SFMBT2. We also found that human SFMBT2 binds(More)
PURPOSE To compare the optical quality measurements obtained from the double-pass system and ocular aberrations, subjective visual acuity, and contrast sensitivity score in pseudophakic eyes. METHODS Three months after cataract surgery, modulation transfer function (MTF) cutoff frequency, Strehl ratio, objective scatter index, and objective(More)