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Aiming at the difficulty of choosing filtering parameters of Non-Local Means (NLM) denoising algorithm for Cone-Beam Computed Tomography (CBCT) projection images, an adaptive NLM denoising algorithm is proposed. First, a simplified noise estimation method based on sub-block division is proposed to replace the approach of designating the background region,(More)
The depth distributions of refractive index (RI) in normal and early degenerated articular cartilage (AC) were measured and correlated to the pathological statuses. Utilizing a confocal microscope, the depth distribution of RI was determined with an interval of 50 μm from the articular surface and approximated as a smooth curve. The fluctuation of RI was(More)
Utilizing a laser scanning confocal microscope system, the refractive indices of articular cartilage (AC) with mechanical or biochemical degenerations were characterized to investigate whether potential correlations exist between refractive index (RI) and cartilage degeneration. The cartilage samples collected from the medial femoral condyles of kangaroo(More)
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