Kush Srivastava

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Infection of the eye by Pseudomonas aeruginosa can result in corneal inflammation (keratitis) and ulceration, and permanent decrease in vision if not successfully treated. We tested for diversity among P. aeruginosa strains from corneal ulcers by the sensitive and efficient 'RAPD' (for 'random amplified polymorphic DNA') fingerprinting method. This method(More)
The importance of peptides as therapeutics has been recognized since they were found responsible for a wide variety of biological functions. The recent approval of peptide drugs such as Byetta (Amylin Pharmaceuticals, Inc.), Fuzeon (Hoffman-LaRoche Inc.), Integrelin (CDR Therapeutics, Inc.), Natrecor (SCIOS Inc.), Symlin (Amylin), Teriparatide, and(More)
An ability to distinguish individual strains of Helicobacter pylori with sensitivity and efficiency is valuable for studies of the epidemiology, population genetic structure, and evolution of this gastric pathogen. The arbitrarily primed polymerase chain reaction (AP-PCR), or random amplified polymorphic DNA (RAPD) method (1-4), provides one of the most(More)
Helicobacter pylori is an extremely diverse species. The characterization of strains isolated from individual patients should give insights into colonization and disease mechanisms and bacterial evolution. We studied H. pylori isolates from patients in the Japanese-Peruvian Polyclinic in Lima, Peru, by determining metronidazole susceptibility or resistance(More)
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