Kurt Malberg

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Endometriosis, a benign gynecologic disorder, occurs in about 10% of women in reproductive age and in up to 50% of women with infertility. The basic etiologic factors causing this disease are unknown as yet. Matrix metalloproteinases (MMP) are involved in degradation of the extracellular matrix (ECM). Their proteolytic activity is regulated by tissue(More)
Fc receptor mediated immune complex clearance function was measured in patients with systemic lupus erythematosus. Autologous erythrocytes were sensitized by human IgG anti-Rh(D) and used as immune complex model. An impaired Fc receptor function was demonstrable in 20 of 25 investigated patients. We have found a significant correlation between the(More)
It is given a short report about the principles of the transplantation immunity and the mechanism of the organ transplant rejection. The possibilities to inhibit the transplant rejection (donor-host-selection, antigenicity of the transplant, unspecific and specific immunosuppression: immune tolerance, enhancement) are explained in detail. Finally the(More)
Three methods for immune complex detection were used on 85 women who took oral contraceptives and on 21 who took none to test their sera for circulating immune complexes. The methods were ammonium sulphate precipitation as proposed by Beaumont et al., polyethylene glycol precipitation, and the 125J-Clq fixation test. - Significant rise in precipitable(More)