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PURPOSE Older adults are vulnerable to chemotherapy toxicity; however, there are limited data to identify those at risk. The goals of this study are to identify risk factors for chemotherapy toxicity in older adults and develop a risk stratification schema for chemotherapy toxicity. PATIENTS AND METHODS Patients age ≥ 65 years with cancer from seven(More)
The antennal olfactory receptors of the predatory clerid beetle,Thanasimus formicarius (L.), are as sensitive as the receptors of its prey, the scolytid beetleIps typographus (L.), to ipsdienol, (S)-cis-verbenol and 2,3,2-methylbutenol, suggested components of the aggregation pheromone of this bark beetle. The two species were stimulated under identical(More)
INTRODUCTION This study evaluated the association between aromatase inhibitor (AI) therapy and cognitive function (over a 6-month period) in a cohort of patients aged ≥ 60 years compared with an age-matched healthy control group, and it evaluated changes in regional cerebral metabolism as measured by positron emission tomography (PET) scans of the brain(More)
PURPOSE Factors captured in a geriatric assessment can predict morbidity and mortality in older adults, but are not routinely measured in cancer clinical trials. This study evaluated the implementation of a geriatric assessment tool in the cooperative group setting. PATIENTS AND METHODS Patients age ≥ 65 with cancer, who enrolled on cooperative group(More)
PURPOSE To determine the predictors of distress in older patients with cancer. PATIENTS AND METHODS Patients age >or= 65 years with a solid tumor or lymphoma completed a questionnaire that addressed these geriatric assessment domains: functional status, comorbidity, psychological state, nutritional status, and social support. Patients self-rated their(More)
OBJECTIVE To determine risk factors for lack of recovery of independent functioning after hospitalization for acute medical illness. DESIGN Secondary analysis of cohort study of patients receiving home nursing after discharge. SETTING Evaluations performed in the home after discharge and 1 month later. PARTICIPANTS A total of 73 adults aged 65 years(More)
BACKGROUND Little is known about complementary medication use among older adults with cancer, particularly those who are receiving chemotherapy. The objective of this study was to evaluate the prevalence of complementary medication use and to identify the factors associated with its use among older adults with cancer. METHODS The prevalence of(More)
BACKGROUND Bevacizumab leads to improved survival for patients with metastatic colorectal cancer (CRC) or non-small cell lung cancer (NSCLC) when added to chemotherapy. Little is known about factors associated with receipt of bevacizumab, or whether bevacizamab is associated with increased toxicity when added to chemotherapy. PATIENTS AND METHODS We(More)
For spills of submerged oil, current methods are inadequate to find and recover the oil. Many of the detection approaches are ad-hoc and the recovery techniques very labor intensive. The Coast Guard R&D center has embarked on a multi-year project to develop a complete approach for spills of submerged oils. This paper describes the preliminary assessment of(More)
The rate of return migration to the South rose by nearly 19 percent between the late 1950's and the late 1960's and was an important factor in changing the South's overall migration pattern. But an increase in the rate of return migration was somewhat less important in changing Southern migration than (1) a decline in the rate of out-migration of native(More)