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Using extracorporeal life support to resuscitate adult postcardiotomy cardiogenic shock: treatment strategies and predictors of short-term and midterm survival.
TLDR
An age of >60 years, a necessity for postoperative continuous arteriovenous hemofiltration, a maximal serum total bilirubin >6 mg/dL, and a need for ECLS support for >110 h were independent predictors of in-hospital mortality. Expand
Blunt traumatic cardiac rupture: therapeutic options and outcomes.
TLDR
A protocol combining various diagnostic tools, including FAST, CT, transthoracic echocardiography, and TEE, is proposed to manage suspected blunt traumatic cardiac rupture in patients confirmed with blunt thoracic trauma. Expand
Biodegradable cisplatin-eluting tracheal stent for malignant airway obstruction: in vivo and in vitro studies.
TLDR
It is demonstrated that the biodegradable stents provided physical properties comparable to the properties of SEMSs and a sustained release of cisplatin for >5 weeks, which showed great potential in the treatment of malignant airway obstruction. Expand
Risk factors associated with postoperative sore throat after tracheal intubation: an evaluation in the postanesthetic recovery room.
TLDR
Five risk factors related to postoperative sore throat were identified in patients undergoing endotracheal general anesthesia and they were female gender, age between 30-39, surgical sites within the oral or nasal cavity, or around the neck, use of nitrous oxide during anesthesia, and duration of anesthesia longer than 2 hours. Expand
Lipid nanoparticles with different oil/fatty ester ratios as carriers of buprenorphine and its prodrugs for injection.
TLDR
The results indicate the feasibility of using lipid nanoparticles, especially SLNs and NLCs, as parenteral delivery systems for buprenorphine and its prodrugs. Expand
Enhancement of transdermal apomorphine delivery with a diester prodrug strategy.
TLDR
The results in the present work suggest the feasibility of diester prodrugs for the transdermal delivery of apomorphine and exhibited superior skin permeation compared to the parent drug when formulated into the emulsions. Expand
Novel Biodegradable Polycaprolactone Occlusion Device Combining Nanofibrous PLGA/Collagen Membrane for Closure of Atrial Septal Defect (ASD)
TLDR
To manufacture the biodegradable occlusion devices for closure of atrial septal defects (ASD), polycaprolactone components were first fabricated by a lab-scale micro-injection molding machine and hot-spot welded into double umbrella-like devices of 50 mm in diameter. Expand
Simultaneous determination of buprenorphine and its prodrug, buprenorphine propionate, by high-performance liquid chromatography with fluorescence detection: application to pharmacokinetic studies in
TLDR
A rapid, sensitive, precise and accurate high-performance liquid chromatographic assay with fluorescence detection was developed and demonstrated that buprenorphine propionate was rapidly and totally converted to its parent drug, bupenorphine, following intravenous administration. Expand
Postcardiotomy Extracorporeal Life Support in Adults: The Optimal Duration of Bridging to Recovery
TLDR
The optimal ECLS duration for myocardial recovery was defined as the supporting time of survivors, and Bridging should be considered in suitable patients having ECRS >7 days or showing instabilities under an adequate ECLs >24 hours. Expand
Topically applied mesoridazine exhibits the strongest cutaneous analgesia and minimized skin disruption among tricyclic antidepressants: The skin absorption assessment.
TLDR
Meridazine showed stronger skin analgesia than the other TCAs although the in vivo skin absorption of mesoridazine was less than that of promazine and doxepin, and the follicular pathway was important for mes oridazine and promazine delivery. Expand
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