Kuniko Sekihara

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BACKGROUND The phase II NEJ001 trial suggested that gefitinib was active against advanced non-small cell lung cancer (NSCLC) even in patients with poor performance status (PS). Clinical response among the patients harboring epidermal growth factor receptor (EGFR) mutation with poor PS is fair; however, gefitinib does not have as much continued efficacy as(More)
Serum gamma-GTP measurements in 11,755 Japanese men were used to test the hypothesis that drinking whisky had little or no effect on the serum level of this enzyme. We found that regular drinking was associated with significantly increased mean levels and raised percentages of high values of gamma-GTP, irrespective of the type of alcohol consumed. Moreover,(More)
An asymptomatic 67-year-old man was referred to our clinic because of an abnormal shadow found on a chest Xray (Picture 1). Chest computed tomography showed the gloved finger sign, thus suggesting mucoid impaction (Picture 2). The lesion was diagnosed to be malignant melanoma by transbronchial lung biopsy (Picture 3). The patient was diagnosed to have(More)
Thymic carcinoma is a rare type of cancer, which arises from the thymic epithelium and accounts for ~1-4% of anterior mediastinal tumors in the USA. It rarely occurs in children, and is rarer among adults. Thymic lymphoepithelioma-like carcinoma (LELC) is an uncommon subtype of thymic carcinoma in children, however, it is one of the common histological(More)
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