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The present study was focused on evaluating the potential of Emblica officinalis against cariogenic properties of Streptococcus mutans, a causative microorganism for caries. The effect of crude extract and ethanolic fraction from Emblica officinalis fruit was analysed against S. mutans. The sub-MIC concentrations of crude and ethanolic fraction of E.(More)
OBJECTIVES To evaluate the synergistic effect of Quercitrin and Deoxynojirimycin (DNJ) together with their individual inhibitory effect against virulence pathways of Streptococcus mutans. METHODOLOGY MICs of both the compounds were determined by the microdilution method, followed by their in vitrosynergy using checkerboard and time kill assay. The nature(More)
Ascochyta blight caused by the ascomycete fungus Ascochyta rabiei, is a major biotic constraint of chickpea (Cicer arietinum L.), resulting in disastrous crop losses worldwide. To study early stages of development and pathogenic mechanisms of the fungus, two binary vectors for the constitutive expression of the red fluorescent protein (DsRed-Express) and(More)
Localized cell death, known as the hypersensitive response (HR), is an important defense mechanism for neutralizing phytopathogens. The hallmark of the HR is an oxidative burst produced by the host plant. We aimed to identify genes of the necrotrophic chickpea blight fungus Ascochyta rabiei that are involved in counteracting oxidative stress. A subtractive(More)
We define Pathomics as the process of high throughput generation, interrogation, and mining of quantitative features from high-resolution histopathology tissue images. Analysis and mining of large volumes of imaging features has great potential to enhance our understanding of tumors. The basic Pathomics workflow consists of several steps: segmentation of(More)
Marine Bacillus species are potent producers of novel enzymes. Marine Bacillus VITRKHB was observed to be efficient for cellulolytic activity. It was employed for the production of extracellular cellulase. Cellulase was partially purified to 1.6-fold in a stepwise manner by ammonium sulfate precipitation, dialysis, and DEAE ion exchange chromatography. The(More)
Streptococcus mutans is well documented as a major aetiological agent of dental caries. The ability to form a biofilm on tooth surfaces is the major virulence factor of this bacterium. The objective of this study was to evaluate the effect of eugenol on suppression of biofilm- and quorum sensing (QS)-related genes of S. mutans and to determine its putative(More)
A graphical password system with a supportive sound signature and video clip to enhance the security level in authentication system and it is cued click point based system. In this system password consist of graphical images in which user can select one cued click-point per image and video clip for authentication. Systems shared very good performance in(More)
Old Yellow Enzyme (OYE1) was the first flavin-dependent enzyme identified and characterized in detail by the entire range of physical techniques. Irrespective of this scrutiny, true physiological role of the enzyme remains a mystery. In a recent study, we systematically identified OYE proteins from various fungi and classified them into three classes viz.(More)
One of the oldest patient communities on Twitter is characterized by the hashtag #bcsm, and it is a forum for breast cancer patients and survivors. This community has been hosting a weekly, moderated chat for the last three years. This paper describes work that analyzes the content of these chats and explores their effectiveness for the patients. The(More)