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ProCoS is a free online tool for computing different combinations of peptide compositions. It is developed as an applet and a server with a capability to handle multiple FASTA sequences. The generalized algorithm for computing poly-amino acid composition forms the core of ProCoS. It produces output in different formats for easy visualization of results. It(More)
HIV is one of the most dreaded diseases of the century. Throughout the world efforts are underway to develop new vaccines and design new drugs so as to combat this viral menace. In an effort to probe deeper into the functioning of these viruses we present association based rules formulation so as to decipher the most frequently occurring amino acids in(More)
The cyclin-dependent kinases (Cdks) are a family of serine/threonine protein kinases whose members are small proteins (∼34–40 kDa) composed of little more than the catalytic core shared by all protein kinases. All Cdks share the feature that their enzymatic activation requires the binding of a regulatory cyclin subunit. Various combination of(More)
Mycobacterium tuberculosis (MTB), causative agent of tuberculosis, is one of the most dreaded diseases of the century. It has long been studied by researchers throughout the world using various wet-lab and dry-lab techniques. In this study, we focus on mining useful patterns at genomic level that can be applied for in silico functional characterization of(More)
—GPCRs or G Protein Coupled Receptors are very important molecules and are implicated not only in normal physiological processes but also in diseases. Around 40% of the drugs in the market are targeted towards GPCRs. Through out the world various attempts have been made to analyze and understand these molecules using various attributes and algorithms but(More)
The MMPs and ADAMs are cell surface proteases which belong to metalloprotease family. They play an important role in skin aging, skin disorders, anticancer therapy and other physiological disorders. Thus there arises the need to understand the relationships among various parameters of these proteins for prediction of their classes, structures and(More)
Various combination of both cyclin dependent kinases (CDKs) and cyclin proteins are responsible for progression of cell cycle through various phases like G1, S, G2 and M. CDKs are enzymes with possible role to play in anti cancer therapy. Realizing the importance of both these proteins in various aspects of life a new efficient computational model has been(More)
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