Kumiko Uryu

  • Citations Per Year
Learn More
We describe the results from a protein-based approach to the study of heterogeneity in gene expression between human tumors. Cell preparations from 5 benign breast lesions, 5 potentially weakly malignant and 4 potentially highly malignant invasive ductal breast carcinomas were examined by 2-dimensional gel electrophoresis (2-DE) gels. Qualitative and(More)
Sample preparation procedures are critical for obtaining high quality two-dimensional electrophoresis (2-DE) separations from clinical tumor materials. In this communication, we describe procedures which we have found satisfactory for preparing various tumor samples for 2-DE. By these procedures, tumor cells are enriched from serum proteins and(More)
A. Borthakur, K. Uryu, S. B. Shively, H. Poptani, M. Corbo, S. R. Charagundla, J. Q. Trojanowski, V. M. Lee, R. Reddy University of Pennsylvania, Philadelphia, PA, United States Synopsis Early in its disease progression, Alzheimer’s disease (AD) is characterized by the formation of amyloid (i.e. senile) plaques, which are extra-cellular deposits of(More)
High-dose methotrexate (HD-MTX) is an important treatment for Burkitt lymphoma, but can cause hepatic and renal toxicity when its clearance is delayed. We report a case of acute renal failure after HD-MTX therapy in a patient with ileostomy, The patient was a 3-year-old boy who had received a living-related liver transplantation for congenital biliary(More)
  • Kumiko Uryu
  • [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai
  • 1995
The purpose of this introducing study was to establish the normal lung density using computed tomography of the chest. If it is possible to analyze the density of normal lung parenchyma, it could be possible to estimate the quantity of effective ventilation capacity based on account of the CT number of given range. A cross section of the lung, however, is(More)
We report a sixteen-year-old boy with Down syndrome and relapse of AML (M7), who has been in complete remission (CR) more than 12 months after bone marrow transplantation (BMT) from an HLA-matched sibling donor. Because monosomy 7 was detected at onset of AML and he experienced relapse after the treatment of AML 99 Down protocol, his prognosis was(More)
Background Neuroblastoma (NB) is the most common solid tumor found in children, and deletions within the 11q region are observed in 11% to 48% of these tumors. Notably, such tumors are associated with poor prognosis; however, little is known regarding the molecular targets located in 11q. Methods Genomic alterations of ATM , DNA damage response(More)
  • 1