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Copper electrodes for stable subpicomole detection of carbohydrates in high-performance liquid chromatography
Abstract A new pretreatment of copper (Cu) electrodes used for catalytic oxidation of carbohydrates is presented, which involves superficial polishing of the electrochemically-oxidized Cu electrodeExpand
Electrochemicolor Imaging Using an LSI-Based Device for Multiplexed Cell Assays.
The imaging system is successfully applied for detecting multiple cell functions of the embryonic stem cell and the rat pheochromocytoma cell aggregates and is the first time that a real-time electrochemical mapping technique for multiple electroactive species, simultaneously, has been reported. Expand
A competitive immunochromatographic assay for testosterone based on electrochemical detection.
An immunochromatographic assay using nitrocellulose membrane was combined with electrochemical detection using an electrode chip in order to quantitatively detect testosterone as a model analyte. TheExpand
Electrochemical detection of endotoxin using recombinant factor C zymogen
Abstract We have developed a zymogen-based electrochemical sensor. Zymogen is an inactive enzyme precursor (proenzyme) and it is necessary to transform it biochemically (e.g., by hydrolysis andExpand
Electrochemical sensor with substitutional stripping voltammetry for highly sensitive endotoxin assay.
Extra-highly sensitive detection of p-aminophenol liberated by the endotoxin-induced LAL reaction was successfully realized with SSV, based on the accumulation of an amperometric signal owing to exchange of the oxidation current of pAP generated at an electrodes in a reaction cell with silver deposition on another electrode in a deposition cell. Expand
Novel electrochemical methodology for activity estimation of alkaline phosphatase based on solubility difference.
Using this novel system, the ALP activity of embryoid bodies was successfully detected and it is believed that the present system will be widely applicable to ALP-based bioassays. Expand
Electrochemical Imaging of Dopamine Release from Three-Dimensional-Cultured PC12 Cells Using Large-Scale Integration-Based Amperometric Sensors.
This report is the first to describe electrochemical imaging of dopamine release by PC12 spheroids using LSI-based amperometric sensors, suggesting that the Bio-LSI is a promising tool for use in evaluating 3D-cultured dopamine cells and the effects of dopaminergic drugs. Expand
Electrochemical approach for the development of a simple method for detecting cell apoptosis based on caspase-3 activity.
This novel electrochemical apoptosis assay using living cells instead of typically used cell lysates will expand the applicable range of the apoptosis assays to include cell activity assays for drug discovery and cell transplantation medicine. Expand
Development of an electrochemical Limulus amebocyte lysate assay technique for portable and highly sensitive endotoxin sensor
An electrochemical detection method based on the Limulus amebocyte lysate (LAL) assay that appears promising for the development of compact, low-cost and easy-to-use sensors for on-site monitoring of potentially contaminated medical supplies, including dialysis fluid, transplanted tissue and culture medium for assisted reproduction. Expand
LSI-based amperometric sensor for bio-imaging and multi-point biosensing.
An LSI-based amperometric sensor with 400 measurement points as a platform for electrochemical bio-imaging and multi-point biosensing with a wide dynamic range from ±1 pA to ±100 nA with a well-organized circuit design and operating software is developed. Expand