Kuiliang Jiao

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A new microemulsions system of curcumin (CUR-MEs) was successfully developed to improve the solubility and bioavailability of curcumin. Several formulations of the microemulsions system were prepared and evaluated using different ratios of oils, surfactants, and co-surfactants (S&CoS). The optimal formulation, which consists of Capryol 90 (oil), Cremophor(More)
The serum zinc levels and urinary zinc outputs before and after a middle severity operative trauma were investigated. The serum zinc concentration dropped markedly 6 hr after operation in both supplemented and nonsupplemented groups. It gradually returned to near normal without exogenous supplies of zinc. Provision of therapeutic doses of zinc could not(More)
Bilateral electrical lesioning of the hippocampal CA3 region (HCA3-EL) or anterior commissura hippocampi (ACHF-EL) caused marked elevations in plasma basal levels of insulin. 2 weeks later, fasting blood glucose levels were also augmented with decreased glucose tolerance. In contrast, the secretory response of pancreatic B cells to glucose stimulation was(More)
Solid dispersion technique has been developed many years for improving solubility of water-insoluble drugs, aiming to achieve a better oral bioavailability. However, this technique exhibits many inconveniences when used for large-scale tableting procedures. The objective of current research work was to develop cilnidipine solid dispersions (SDs) to improve(More)
The effect of gama-aminobutyric acid (GABA) on release of adrenocorticotropin (ACTH) from anterior pituitary quarters of male SD rats adrenalectomized for 96 hrs was investigated using the perfusion technique in vitro. Application of bicuculline (10(-6)mol/L), a specific GABA-A antagonist, resulted in a significant release of ACTH from perfused anterior(More)
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