Kuang-Chong Wu

Learn More
A new technique is developed to measure the nanoparticles' brownian motions by employing microparticle-tracking velocimetry (micro-PTV) in evanescent wave field, which can provide high signal-to-noise ratio images for analyzing nanoparticles' movements. This method enables real-time detection of C-reactive proteins (CRPs) during the rapid interaction(More)
A novel bio-sensing technique based on the measurement of nanobeads' Brownian motion using a micro-particle tracking velocimetry (micro-PTV) has been successfully developed to detect antigen-antibody interactions. The rapid interaction between antigens (C-reactive proteins, CRPs) and nanobeads with conjugated antibodies (anti-CRPs) has enabled real-time(More)
The effect of coupled mode surface plasmon polaritons (SPPs) on the active emission of a nanostructure grating with organic semiconductor material, Alq(3), on the surface was investigated in this study. We report surface plasmon grating coupled emission (SPGCE) from excited organic layer on metal grating in both organic/metal (2-Layer) and(More)
A set of innovative phase-shifting algorithms developed to facilitate metrology based on electronic speckle pattern interferometry (ESPI) are presented. The theory of a phase-shifting algorithm, called a (5,1) algorithm, that takes five phase-shifted intensity maps before a specimen is deformed and one intensity map after a specimen is deformed is presented(More)
A circularly polarized ellipsometer was developed to enable real-time measurements of the optical properties of materials. Using a four photo-detector quadrature configuration, a phase modulated ellipsometer was substantially miniaturized which has the ability to achieve a high precision detection limit. With a proven angular resolution of 0.0001 deg(More)
We investigate a immunoassay biosensor that employs a Quartz Crystal Microbalance (QCM) to detect the specific binding reaction of the (Human IgG1)-(Anti-Human IgG1) protein pair under physiological conditions. In addition to experiments, a three dimensional time domain finite element method (FEM) was used to perform simulations for the biomolecular binding(More)
Micro-cantilever sensors are widely used to detect biomolecules, chemical gases, and ionic species. However, the theoretical descriptions and predictive modeling of these devices are not well developed, and lag behind advances in fabrication and applications. In this paper, we present a novel multiscale simulation framework for nanomechanical sensors. This(More)
We investigated the process of focusing a radially polarized (RP) light beam through a sub-wavelength annular aperture (SAA). We found that the result was a non-diffraction doughnut-shaped light beam which propagates in free space. After analyzing the electric field component of the focus generated by the SAA structure, we identified the relationship(More)
Although, photorefractive materials have been discovered for many years, research using pulsed laser as the light source and photorefractive material as the recording media to record a pulsed laser hologram have been scarce despite its vast application potential. A newly proposed optical configuration which adopts a Nd:YAG pulsed laser of 532nm wavelength(More)
This paper deals with the vibration analysis of an asymmetric composite beam composed of glass a piezoelectric material. The Bernoulli’s beam theory is adopted for mechanical deformations, and the electric potential field of the piezoelectric material is assumed such that the divergence-free requirement of the electrical displacements is satisfied. The(More)