Ku-chou Chang

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BACKGROUND The effect of oxygen therapy in acute ischemic stroke remains undetermined. OBJECTIVE To investigate the feasibility of eubaric hyperoxia therapy by Venturi mask (VM) in a group of patients who experienced a severe acute ischemic stroke. DESIGN Patients experiencing a first-ever large middle cerebral artery infarction were recruited within 48(More)
OBJECTIVE For 3,670 stroke patients from the United Kingdom, United States, Australia, Belgium, and Italy, we performed a genome-wide meta-analysis of white matter hyperintensity volumes (WMHV) on data imputed to the 1000 Genomes reference dataset to provide insights into disease mechanisms. METHODS We first sought to identify genetic associations with(More)
OBJECTIVE We aimed to report 3-year survival and causes of death of first-ever ischemic stroke stratified by initial stroke severity. STUDY DESIGN AND SETTING From September 1998 to October 1999, 360 acute first-ever ischemic stroke patients consecutively admitted were followed up prospectively. Patients' vital status and causes of death were identified(More)
OBJECTIVE Cost-effectiveness analysis (CEA) of stroke management was evaluated in three care models: Neurology/Rehabilitation wards (NW), Neurosurgery wards (NS), and General/miscellaneous wards (GW) under a universal health insurance system. METHODS From 1997 to 2002, subjects with first-ever acute stroke were sampled from claims data of a nationally(More)
OBJECTIVE There is insufficient evidence on which to base a recommendation for optimal antiplatelet therapy following a stroke while on aspirin. The objective was to compare clopidogrel initiation vs aspirin reinitiation for vascular risk reduction among patients with ischaemic stroke on aspirin at the time of their index stroke. DESIGN Retrospective. (More)
PURPOSE This work was undertaken to review current evidence of cost-effectiveness analysis (CEA) on thrombolysis for acute ischemic stroke. METHODS An electronic search via PubMed, from 1995 until May 2004, was performed. The methods undertaken by these studies were examined with particular attention to their modeling assumptions, sources of data, and(More)
BACKGROUND This study searches the National Health Insurance Research Database (NHIRD) used in a previous project, aiming for reconstructing possible cerebrovascular disease-related groups (DRG),and estimating the costs between cerebrovascular disease and related diseases. METHODS AND MATERIALS We conducted a nationwide retrospective cohort study in(More)
To reduce the health care burden of strokes, the Taiwan Department of Health launched the Pilot Scheme of the Health Policy in Stroke Adjuvant Acupuncture Therapy (HPSAAT) in 2006. This cross-sectional, hospital-based, match-controlled study at Chang Gung Memorial Hospital-Kaohsiung Medical Center during 2006∼2008 retrospectively evaluated the clinical(More)
BACKGROUND AND PURPOSE Stroke is one of the causes of prolonged hospital stay (PHS) in Taiwan. This study aimed to examine the magnitude and associated factors for such prolonged stays. METHODS Patients admitted between 1997 and 2002 with the principal diagnosis of acute cerebrovascular diseases were identified from the claims data of a nationally(More)