Krzysztof Wnuczko

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Mucin 1 (MUC1) is a membrane-bound glycoprotein that is expressed by various epithelial cell types. MUC1 functions include modulation of cell adhesion, signal transduction, lubrication and hydration of epithelial surfaces, and their protection from infection. In this study we demonstrated that MUC1 is expressed in human umbilical vein endothelial cells(More)
Endothelium is more and more likely to be considered as the biggest endocrine gland of human body. According to number, mass, surface of endothelial cells in adolescent, ability of synthesis and release of substances with multidirectional biological functions, endothelium should be treated as integral organ. Endothelial cells form barrier between blood and(More)
PURPOSE The expression of FasR, Fas-L and Bcl-2 on CD4+ and CD8+ T lymphocytes subpopulations from the cord blood were assayed. The results in blood from boys and girls were analyses separately and compared. MATERIAL AND METHODS Twenty four full-term newborns: 13 females and 11 males were included into the study. Blood from the umbilical vein was(More)
The aim of this study was to investigate the influence of epigallocatechin-3-gallate (EGCG), theaflavins (TFs) and black tea extract (BTE) on oxidative stress formation as well as on antioxidant system of human vein endothelial cells (HUVEC). HUVEC were incubated for 0,5 h with 100 mM tert-butyl hydroperoxide (t-BHP) for oxidative stress formation. The(More)
UNLABELLED The latest research proved that erythropoietin (Epo), a sensitive to hypoxia physiological erythropoiesis regulator, used successfully to treat anemia, displays cytoprotective, angiogenic, anti-inflammatory, anti-oxidative and anti-apoptotic properties. The aim of the study was to examine the influence of Epo on intercellular adhesion molecule-1(More)
UNLABELLED According last research erythropoietin (Epo), glycoprotein known as a physiological regulator of erythropoiesis and used successfully to treat anemia, displays cytoprotective properties. It is supposed that the protective effect of EPO is based on its ability to oxidation-reduction stabilization of cells. AIM The aim of the study was to examine(More)
OBJECTIVES This study aims to asses the effects of estradiol vs. raloxifene on the levels of osteoprotegerin and soluble Receptor Activator of Nuclear Factor kB Ligand (sRANKL) in Human Umbilical Vein Endothelial Cells (HUVEC) culture in standard and calcifying medium. MATERIAL AND METHODS Human Umbilical Vein Endothelial Cells were isolated from human(More)
UNLABELLED Activation, proliferation and regeneration of endothelium form developmental background of many pathological states. In those processes adhesion molecules and growth factors are crucial. Insulin-like growth factor-1 (IGF-1) is important regulator of vascular function, expressing pleiotropic actions. Interactions between endothelial cells and(More)
UNLABELLED Activation, proliferation and regeneration of endothelium form developmental background of many pathological states. In those processes adhesion molecules and growth factors are crucial. Insulin-like growth factor 1 (IGF-1) is an important regulator of vascular function, capable of expressing pleiotropic actions. Interactions between endothelial(More)
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