Krzysztof Szadkowski

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UNLABELLED Serotonin (5-HT) is among other factors involved in gastrointestinal motility, secretion and visceral sensation. Available data suggest that secretion and metabolism of 5-HT may be disturbed in irritable bowel syndrome (IBS). Interpretation of these observations have been hampered by the variable methodology used and small numbers of patients(More)
UNLABELLED The cause and factors determining the chronic course of ulcerative colitis (UC) remain unknown. Melatonin is synthetised in the gastrointestinal tract and plays a crucial role in the protection of gastrointestinal mucosa and modulation of the immune system. Melatonin is metabolised to 6-hydroxymelatonin sulfate (6HMS) and excreted into urine.(More)
BACKGROUND Galectin-3, a biomarker associated with fibrosis and inflammation, has been implicated in development and progression of heart failure (HF) and predicts increased mortality and morbidity in this condition. HF frequently develops after myocardial infarction (MI), contributing to worse outcome. The aim of this study is to assess the association(More)
UNLABELLED The pathogenesis of functional dyspepsia is still not clear. One of the supposed mechanisms are disturbences of motility of upper part of gastrointestinal tract. There only the few informations, concerning the role of retrograde refluxes. AIM OF STUDY Comparative analysis of grade of duodenogastric reflux intensity in healthy subjects and in(More)
CONTEXT Galectin-3, as a biomarker of inflammation and fibrosis, has been reported to be associated with coronary artery disease. OBJECTIVE The study aimed to assess the relationship between galectin-3 levels and the occurrence of reinfarction early after myocardial infarction (MI). METHODS The study included 145 consecutive patients with first MI(More)
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