Krystyna Romańska-Gocka

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Pyoderma gangrenosum (PG) is a non-infectious in-flammatory skin disease, resulting in large ulcers that can spread rapidly showing undermined, violaceous borders and a necrotic, purulent base [1–3]. The etiology remains unclear, but it appears to have an immunologic background [2–4]. It is probably a hyperergic reaction, connected with systemic disorders.(More)
INTRODUCTION The genetic background of atopic dermatitis (AD) is complex, involves many genes and their participation varies in varied populations, and depends on the intensity and course of a disease. Changes in the nucleotide sequence of the FLG gene and a reduced number or a deficit of the functional product of processed profilaggrin can be one of risk(More)
We present a case of Stevens Johnson syndrome in a child after carbamazepine application and Stevens Johnson/TEN overlap syndrome in an adult after amoxicillin application. On the basis of two reported cases we review the most commonly associated drugs, the postulated pathogenesis, clinical manifestation and management in these severe life-threatening(More)
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