Krystyna Romańska-Gocka

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Pyoderma gangrenosum (PG) is a non-infectious in-flammatory skin disease, resulting in large ulcers that can spread rapidly showing undermined, violaceous borders and a necrotic, purulent base [1–3]. The etiology remains unclear, but it appears to have an immunologic background [2–4]. It is probably a hyperergic reaction, connected with systemic disorders.(More)
Acne in adults is a chronic, increasingly common disease, especially among women. It differs in pathogenesis and clinical presentation from adolescent acne. Acne in adults is associated with Western diet, defined as high consumption of milk, high glycemic load and high calorie intake. Metabolic signals of this diet result in a significant increase in(More)
We present a case of Stevens Johnson syndrome in a child after carbamazepine application and Stevens Johnson/TEN overlap syndrome in an adult after amoxicillin application. On the basis of two reported cases we review the most commonly associated drugs, the postulated pathogenesis, clinical manifestation and management in these severe life-threatening(More)
INTRODUCTION During the process of skin ageing, changes occur in all skin layers and all cells, including the Langerhans cells. AIM To assess whether any quantitative difference in the number of CD1a+ LC cells/mm2 and HLA-DR+ LC cells/mm2 as well as in their morphological features can be observed during the course of different types of skin ageing. (More)
INTRODUCTION The genetic background of atopic dermatitis (AD) is complex, involves many genes and their participation varies in varied populations, and depends on the intensity and course of a disease. Changes in the nucleotide sequence of the FLG gene and a reduced number or a deficit of the functional product of processed profilaggrin can be one of risk(More)
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