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Unilateral focal cold blocks (20 degrees C) in structures located ventrolaterally in rostral medulla consistently caused apnoea or deep depression of inspiratory motor output. The inhibitory effect… Continue Reading
This article reviews age-related changes in structural, biochemical, and mechanical properties of skeletal muscles, including the respiratory muscles. An understanding of the mechanisms associated… Continue Reading
The aim of this study was to examine the response of phrenic and hypoglossal motor outputs to hyperoxia and 11% hypoxia during picrotoxin-induced seizures. Adult rats were anesthetized with a mixture… Continue Reading
Unilateral focal cold blocks in the region of the nucleus tractus solitarius and the dorsal respiratory group of neurons, DRG, of anaesthetized cats consistently caused apneustic-type breathing.… Continue Reading
Respiratory disturbances accompany Parkinson's disease. Weakness of the respiratory muscles or lowering of central respiratory drive might be responsible for respiratory disability. Striatal… Continue Reading
Modified non-motor brainstem ventilatory control might be involved in Parkinson's disease. Our study was designed to investigate the impact of degeneration of the nigrostriatal dopaminergic pathway… Continue Reading
Cortical activity and respiratory responses to intermittent hypoxia were studied in anesthetized, paralyzed, vagotomized, and artificially ventilated rats. Respiratory responses to hypoxic exposure… Continue Reading
In rabbits naive to opiates or pretreated with morphine a selective morphine-induced facilitation of the Breuer-Hering inflation reflex is described.
Disinhibition or 'release' of expiratory muscle activity in response to focal cooling of various medullary structures was of two kinds: (1) release of rhythmic expiratory activity even when no such… Continue Reading
A brief period of antecedent oxygen breathing enhances the ventilatory response to hypoxia. The mechanisms of this phenomenon are uncertain and have been variably linked to the central glutamatergic… Continue Reading