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- Krithika Rajagopalan, Steven M Mooney, Nehal Parekh, Robert H. Getzenberg, Prakash A. Kulkarni
- Journal of cellular biochemistry
- 2011
The cancer/testis antigens (CTAs) are a group of heterogeneous proteins that are typically expressed in the testis but aberrantly expressed in several types of cancer. Although overexpression of CTAs… (More)
- Yanan He, Yihong Chen, +7 authors John Orban
- The Journal of biological chemistry
- 2015
Prostate-associated gene 4 (PAGE4) is an intrinsically disordered cancer/testis antigen that is up-regulated in the fetal and diseased human prostate. Knocking down PAGE4 expression results in cell… (More)
- Steven M Mooney, Ruoyi Qiu, +6 authors Keith R. Weninger
- Biochemistry
- 2014
Prostate-associated gene 4 (PAGE4) is a cancer/testis antigen that is typically restricted to the testicular germ cells but is aberrantly expressed in cancer. Furthermore, PAGE4 is developmentally… (More)
- G Pavlinkova, Krithika Rajagopalan, +6 authors Heinz Kohler
- Journal of immunological methods
- 1997
Herein we report a new method to rapidly photoinsert biotin into a specific and highly conserved site on the Ig structure using a mild photochemical activation step. This site resides in the Fv… (More)
- Michael E. Salvucci, Krithika Rajagopalan, Gail A. Sievert, Boyd E. Haley, David S. Watt
- The Journal of biological chemistry
- 1993
The phosphate-binding domain of the ATP-binding site of tobacco Rubisco (ribulose-1,5-bisphosphate carboxylase/oxygenase) activase was elucidated by photo-affinity labeling with a monoanhydride of… (More)
- Krithika Rajagopalan, Ruoyi Qiu, +7 authors Prakash A. Kulkarni
- Biochimica et biophysica acta
- 2014
The Cancer/Testis Antigen (CTA), Prostate-associated Gene 4 (PAGE4), is a stress-response protein that is upregulated in prostate cancer (PCa) especially in precursor lesions that result from… (More)
- Prakash A. Kulkarni, Krithika Rajagopalan, David B. Yeater, Robert H. Getzenberg
- Journal of cellular biochemistry
- 2011
Most proteins encoded by the nuclear genome are synthesized in the cytoplasm and fold into precise 3D structures. During synthesis, the nascent polypeptide begins to fold as it traverses the large… (More)
- Prakash A. Kulkarni, Takumi Shiraishi, Krithika Rajagopalan, Robert Kim, Steven M Mooney, Robert H. Getzenberg
- Nature Reviews Urology
- 2012
Cancer/testis antigens (CTAs) are a group of tumour-associated antigens (TAAs) that display normal expression in the adult testis—an immune-privileged organ—but aberrant expression in several types… (More)
- Krithika Rajagopalan, G Pavlinkova, +4 authors Hanni Kohler
- Proceedings of the National Academy of Sciences…
- 1996
The variable immunoglobulin (Ig) domains contain hypervariable regions that are involved in the formation of the antigen binding site. Besides the canonical antigen binding site, so-called… (More)
- John J. Kim, Krithika Rajagopalan, Basil Hussain, Brenten H Williams, Prakash A. Kulkarni, Steven M Mooney
- Biomarker Research
- 2013
The Cancer Testis Antigens (CTAs) are a group of genes that are highly expressed in the normal testis and several types of cancer. Due to their restricted expression in normal adult tissues, CTAs… (More)