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  • María Elena Luna Morales, Gabriel Rinaldi, Geoffrey N Gobert, Kristine J. Kines, Jose F Tort, Paul J. Brindley
  • Biology, Medicine
  • Molecular and biochemical parasitology
  • 2008 (First Published: 1 February 2008)
  • The aspartic protease cathepsin D (Clan AA, Family A1) is expressed in the schistosome gut where it plays an apical role in the digestion of hemoglobin released from ingested erythrocytes. In thisContinue Reading
  • Mark Sokolowski, Cecily B. DeFreece, Geraldine Servant, Kristine J. Kines, Dawn Deharo, Victoria P. Belancio
  • Biology, Medicine
  • Mobile DNA
  • 2014 (First Published: 1 December 2014)
  • BackgroundLINE-1 (L1) retrotransposons are common occupants of mammalian genomes representing about a fifth of the genetic content. Ongoing L1 retrotransposition in the germ line and somatic tissuesContinue Reading
  • Kristine J. Kines, María Elena Luna Morales, Victoria H Mann, Geoffrey N Gobert, Paul J. Brindley
  • Biology, Medicine
  • FASEB journal : official publication of the…
  • 2008 (First Published: 1 August 2008)
  • The recent release of draft genome sequences of two of the major human schistosomes has underscored the pressing need to develop functional genomics approaches for these significant pathogens. TheContinue Reading
  • Kristine J. Kines, Victoria H Mann, +5 authors Paul J. Brindley
  • Biology, Medicine
  • Experimental parasitology
  • 2006 (First Published: 1 April 2006)
  • Retroviral transduction of cultured schistosomes offers a potential means to establish transgenic lines of schistosomes and thereby to facilitate the elucidation of schistosome gene function andContinue Reading
  • Dawn Deharo, Kristine J. Kines, +7 authors Victoria P. Belancio
  • Medicine, Biology
  • Nucleic acids research
  • 2014 (First Published: 8 July 2014)
  • Expression of long interspersed element-1 (L1) is upregulated in many human malignancies. L1 can introduce genomic instability via insertional mutagenesis and DNA double-strand breaks, both of whichContinue Reading