Kristina Wanieck

Learn More
BRCA1 is a well-known tumor suppressor protein in mammals, involved in multiple cellular processes such as DNA repair, chromosome segregation and chromatin remodeling. Interestingly, homologs of BRCA1 and several of its complex partners are also found in plants. As the respective mutants are viable, in contrast to mammalian mutants, detailed analyses of(More)
In the plant genome a row of homologs of human genes can be found that, if mutated, are correlated with a high incidence of cancer in humans. Here we describe our recent results on homologs of the breast cancer genes BRCA1/BARD1 and RecQ helicase homologs in the model plant Arabidopsis thaliana. HsBRCA1 and HsBARD1 are tumor suppressor proteins that are(More)
  • 1