Kristin A Sepulveda

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RATIONALE Research evaluating acute respiratory failure (ARF) survivors' outcomes after hospital discharge has substantial heterogeneity in terms of the measurement instruments used, creating barriers to synthesizing study data. OBJECTIVES To identify a minimum set of core outcome measures that are essential to include in all clinical research studies(More)
BACKGROUND Effective strategies for contacting and recruiting study participants are critical in conducting clinical research. In this study, we conducted two sequential randomized controlled trials of mail- and telephone-based strategies for contacting and recruiting participants, and evaluated participant-related variables' association with time to survey(More)
RATIONALE Survivors of acute lung injury (ALI) require ongoing health care resources after hospital discharge. The extent of such resource use, and associated costs, are not fully understood. OBJECTIVES For patients surviving at least 2 years after ALI, we evaluated cumulative 2-year inpatient admissions and related costs, and the association of patient-(More)
OBJECTIVE To evaluate the time-varying relationship of annual physical, psychiatric, and quality of life status with subsequent inpatient healthcare resource use and estimated costs. DESIGN Five-year longitudinal cohort study. SETTING Thirteen ICUs at four teaching hospitals. PATIENTS One hundred thirty-eight patients surviving greater than or equal(More)
OBJECTIVE To study the effect of different mail- and phone-based strategies, along with patient- and research-related factors, on the time to contact with research participants. STUDY DESIGN AND SETTING A prospective evaluation of a 12-week standardized protocol (embedded with two randomized trials of mail- and phone-based strategies) for contacting(More)
OBJECTIVES To identify the "core domains" (i.e., patient outcomes, health-related conditions, or aspects of health) that relevant stakeholders agree are essential to assess in all clinical research studies evaluating the outcomes of acute respiratory failure survivors after hospital discharge. DESIGN A two-round consensus process, using a modified Delphi(More)
BACKGROUND Delayed return to work is common after acute respiratory distress syndrome (ARDS), but has undergone little detailed evaluation. We examined factors associated with the timing of return to work after ARDS, along with lost earnings and shifts in healthcare coverage. METHODS Five-year, multisite prospective, longitudinal cohort study of 138(More)
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