Kristian Friedrich

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BACKGROUND IL-13 promotes acute allergic asthma and is discussed to play a role in late asthmatic features such as fibrotic processes and airway remodelling. The contributions of IL-13-mediated mechanisms to subepithelial events related to fibrosis are not yet settled. OBJECTIVE We investigated the impact of IL-13 on lung epithelial cells as apoptotic(More)
Human Cytomegalovirus (HCMV) is a major cause of morbidity and mortality in transplant patients and in fetuses following congenital infection. The glycoprotein complexes gH/gL/gO and gH/gL/UL128/UL130/UL131A (Pentamer) are required for HCMV entry in fibroblasts and endothelial/epithelial cells, respectively, and are targeted by potently neutralizing(More)
Thymic stromal lymphopoietin (TSLP) is a novel inter-leukin-7-like cytokine, which triggers dendritic cell-mediated inflammatory responses ultimately executed by Th2 helper cells. TSLP is a central player in the development of allergic, especially asthmatic symptoms, and has been suggested to represent a missing link in the information flow from(More)
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