Kristian Fossen

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PURPOSE The ROCC study (randomized study comparing ranibizumab to sham in patients with macular edema secondary to central Retinal vein OCClusion [CRVO]) evaluated the short-term effect of intravitreal ranibizumab injections on best-corrected visual acuity (BCVA) and macular edema. DESIGN Prospective, multicenter, randomized, double-masked,(More)
n engl j med 367;25 december 20, 2012 2456 product. This cognitive overload would make beneficiaries deferential to the status quo and discourage them from switching plans. Consequently, markets would not be operating efficiently. Medicare Advantage and the Prescription Drug Benefit are rife with this kind of market failure. As the number of(More)
To the Editor: We report migratory myiasis that occurred during 1991–2012 caused by the reindeer warble fly, Hypoderma tarandi (online Technical Appendix Figures 1, 2,, in 7 tourists to reindeer habitats of northern Scandinavia. We also report 2 additional women (patients 8 and 9), independent of each(More)
PURPOSE To compare the efficacy and safety of bevacizumab (Avastin; F. Hoffmann-La Roche Ltd, Basel, Switzerland) versus ranibizumab (Lucentis; Novartis Pharma AG, Basel, Switzerland) for neovascular age-related macular degeneration (nAMD) after 2 years when using a treat-and-extend protocol. DESIGN Multicenter, randomized, noninferiority trial with a(More)
In a pilot project, telemedicine was used to conduct retinal examinations of diabetic patients in the Alta municipality of Norway. All health-care workers who were involved in the project were interviewed. The ophthalmologists found that the grading of the level of retinopathy was quicker with digital images than with slit-lamp examinations. Fifty patients(More)
PURPOSE Anti-vascular endothelial growth factor (anti-VEGF) therapy effectively inhibits angiogenesis and is now enjoying widespread use in the treatment of age-related macular degeneration (AMD). It may also have a role in the treatment of macular oedema secondary to other conditions. VEGF is a signalling molecule that has a variety of roles, including(More)
The costs of telemedicine screening for diabetic retinopathy were examined in a trial conducted in northern Norway, involving the University Hospital of Tromsø (UHT) and the primary care centre in Alta, approximately 400 km away. In Alta, specially trained nurses examined 42 diabetic patients using a digital camera to obtain images of the retina. The images(More)
PURPOSE The purpose of the present study was to investigate the prevalence of diabetic retinopathy (DR) in Norway and adherence to the Norwegian Guidelines for screening for diabetic eye disease. METHODS Two hundred and ninety-nine people with diabetes were randomly recruited from the patient lists of randomly selected general practitioners from three(More)
BACKGROUND Stickler's syndrome is an autosomal dominantly inherited connective tissue disorder characterised by ocular, orofacial, skeletal and auditory features. The estimated prevalence is 1:10,000. MATERIAL AND METHODS We present a girl with the salient features of Stickler syndrome. Based on a literature search on Medline, we present an overview of(More)
The study is based on autopsies of 86 drug addicts who died during the period 1986-88 after an opiate ingestion. The average postmortal concentration of morphine after ingestion of heroin was 0.88 mumol/l blood, ranging from 0.0 to 3.1 mumol/l, which is substantially lower than values that have been reported from patients receiving morphine intravenously as(More)