Kristen R Swanson

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Diffuse invasion of the brain, an intrinsic property of gliomas, renders these tumours incurable, and is a principal determinant of their spatial and temporal growth. Knowledge of the invasive potential of gliomas is highly desired in order to understand their behaviour in vivo. Comprehensive ex vivo invasion studies including tumours of different(More)
Pachymic acid (PA) is a purified triterpene extracted from medicinal fungus Poria cocos. In this paper, we investigated the anticancer effect of PA on human chemotherapy resistant pancreatic cancer. PA triggered apoptosis in gemcitabine-resistant pancreatic cancer cells PANC-1 and MIA PaCa-2. Comparative gene expression array analysis demonstrated that(More)
Production of 2-hydroxyglutarate by isocitrate dehydrogenase 1 – mutated gliomas: an evolutionary alternative to the Warburg shift? Dear Editor: The past 2 years have seen a flurry of activity surrounding the 2008 discovery of a conserved mutation in isocitrate dehydrogenase 1 (IDH1) in 75% of grade II and III gliomas and a small fraction (12%) of grade IV(More)
  • Tom Enders, Alex Morin, +18 authors Shelley Mckearney
  • 2016
T ransforming health care is a formidable challenge that can only be met through a coordinated response from academic and practice leaders from across the health professions. Nursing recognizes its important role in steering this critical work and maintaining a laser focus on what is best for the public. Advancing Healthcare Transformation: A New Era for(More)
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