Kristýna Vrbová

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Ultrafine particles (UFP, diameter < 100 nm) exposure has already been associated with adverse effects on human health. Spatial distribution of UFP is non-uniform; they concentrate in the vicinity of the source, e.g. traffic, because of their short lifespan. This work investigates spatial distribution of UFP in three areas in the Czech Republic with(More)
BACKGROUND In the past, the first goal of schizophrenia treatment was to reduce psychotic symptoms, mainly positive symptoms. Recently, as a result of an emphasis on patient needs, the concept of quality of life (QoL) has been brought into the treatment. The goal has therefore changed from the alleviation of symptoms to improvement of the patient's(More)
This study used toxicogenomics to identify the complex biological response of human lung BEAS-2B cells treated with organic components of particulate matter in the exhaust of a diesel engine. First, we characterized particles from standard diesel (B0), biodiesel (methylesters of rapeseed oil) in its neat form (B100) and 30% by volume blend with diesel fuel(More)
OBJECTIVE Self-stigma in psychiatric patients is an issue deserving both research and therapeutic attention. The objective of the present study was to evaluate the psychometric properties of a Czech version of the Internalized Stigma of Mental Illness (ISMI) scale assessing the levels of self-stigma in individuals with mental disorders. METHODS It(More)
INTRODUCTION According to recent findings, certain clinical symptoms of patients suffering from affective and anxiety disorder can be related to dissociation. The aim of our study was to examine if the level of dissociation in bipolar affective disorder differed from the level of dissociation in healthy volunteers. METHODS 41 patients suffering from(More)
OBJECTIVE Adherence to treatment of mental disorders is one of the key factors influencing its success and, secondarily, the patients' quality of life and social adaptation. The cross-sectional study of 90 outpatients diagnosed with psychotic disorders aimed at determining if there was a relationship between discontinuation of psychoactive drugs in the(More)
INTRODUCTION: Self-stigma is a gradual process during which a stigmatized person uncritically accesses and integrates negative societal stereotypes towards persons with mental disorders. It has been repeatedly shown that fear of stigma and self-stigma is associated with lower adherence to various medical procedures. METHOD: 33 outpatients with bipolar(More)
INTRODUCTION Self-stigma plays a role in many areas of the patient's life. Furthermore, it also discourages therapy. The aim of our study was to examine associations between self-stigma and adherence to treatment and discontinuation of medication in patients from various diagnostic groups. METHODS This cross-sectional study involved outpatients attending(More)
OBJECTIVE Beck anxiety inventory (BAI) is widely used self-rating questionnaire evaluating the severity of anxiety symptoms. The aim of our study was to confirm validity and reliability of Czech version of BAI, identify cut-off points and prove sensitivity to measure improvement after therapy. METHODS The patients selected for the study were treated in(More)
Several controlled studies indicate that cognitive behavioral interventions, in conjunction with antipsychotic medication, reduce positive psychotic symptoms in acute as well as chronic schizophrenia. However, a recent review found that CBT did not reduce relapse and readmission compared to standard care. Nevertheless there is a need for searching for new(More)