Krishnan Sureshkumar

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Two specimens of Valenciennea helsdingenii (Bleeker, 1858) were collected off Punnakayal coast, from Gulf of Mannar, southeast coast of India in November 2012. The morphometric and meristic characters of the recorded specimens are described and discussed. This is the first record of the species from the Indian waters that is a range extension of its known(More)
The dissolution and subsequent oral bioavailability of acyclovir (ACY) is limited by its poor aqueous solubility. An attempt has been made in this work to provide mechanistic insights into the solubility enhancement and dissolution of ACY by using the water-soluble carrier polyethylene glycol 6000 (PEG6000). Solid dispersions with varying ratios of the drug(More)
OBJECTIVE The objective of this study is to provide a mechanistic insight into solubility enhancement and dissolution of acyclovir (ACY) by polyethylene glycol20000 (PEG20000). MATERIALS AND METHODS Solid dispersions with differing ratios of drug (ACY) and carrier (PEG20000) were prepared and evaluated by phase solubility, in vitro release studies,(More)
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