Krishnan Kannabiran

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Ticks and mosquitoes are ectoparasitic arthropods that can transmit a variety of diseases to humans and animals during blood feeding and causing serious infectious disorders. The purpose of the present study was to assess the acaricidal and insecticidal property of ethyl acetate extract and its compounds isolated from marine actinobacteria, Streptomyces(More)
The aim of the present study was to assess the larvicidal property of marine actinobacterial compound 5-(2,4-dimethylbenzyl) pyrrolidin-2-one (DMBPO) extracted and isolated from Streptomyces VITSVK5 sp. tested against the larvae of Rhipicephalus (Boophilus) microplus Canestrini (Acari: Ixodidae), Anopheles stephensi Liston, and Culex tritaeniorhynchus Giles(More)
The aim of the present study was to assess the acaricidal and larvicidal property of marine actinobacterial compound (2S,5R,6R)-2-hydroxy-3,5,6-trimethyloctan-4-one extracted and isolated from Streptomyces sp. VITDDK3 tested against the larvae of Rhipicephalus (Boophilus) microplus Canestrini (Acari: Ixodidae), Anopheles subpictus Grassi and Culex(More)
OBJECTIVE To evaluate the leishmanicidal activity of saponin, dasyscyphin C of Eclipta prostrata and sapogenin, gymnemagenol from Gymnema sylvestre leaves under in vitro conditions. MATERIALS AND METHODS Dasyscyphin C/Gymnemagenol were dissolved in phosphate buffered saline (PBS) and diluted with liquid medium to obtain concentrations ranging from 1000 to(More)
BACKGROUND Pharmacological screening and usage of natural products for the treatment of human diseases has had a long history from traditional medicine to modern drugs. The majority of modern drugs are reported to be mostly from natural products. OBJECTIVE The aim of the present study was to evaluate the inhibitory activity of 5-(2,4-dimethylbenzyl)(More)
The aim of the present study was to isolate antibacterial compound from Streptomyces sp. VITMK1 isolated from mangrove soil of Pichavaram, Tamil Nadu, India. A total of 31 actinomycetes isolates were isolated from soil samples collected at the mangrove region. Actinomycetes isolates were screened for antibacterial activity by well diffusion method. The(More)
Actinomycetes were isolated from marine sediment samples collected from the east coast of Chennai, Tamil Nadu, India. Well diffusion and agar plug methods were used for the evaluation of antibiotic production by these isolates against drug resistant Methicillin- resistant Staphylococcus aureus (MRSA) and vancomycin resistant Enterococci (VRE). The potential(More)
The antimicrobial activity of Hemidesmus indicus, Ficus bengalensis and Pterocarpus marsupium roxb was evaluated against pathogenic bacteria Stahylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumonia in an in vitro condition. Aqueous extracts from roots of H. indicus and barks of F. bengalensis and P. marspium roxb were tested for antimicrobial(More)
OBJECTIVE To evaluate the antidiabetic activity of an aqueous extract of the roots of Hemidesmus indicus on blood glucose, serum electrolytes, serum marker enzymes, liver microsomal P-450 enzymes, and lipid peroxidation in the liver and kidney of streptozotocin-induced diabetic rats. MATERIALS AND METHODS Effect of H. indicus extract on blood glucose was(More)
Marine bacteria are considered as imperative source for novel antibacterial compounds. The marine Streptomyces species was isolated from the sediment sample collected at the coast of Andaman and Nicobar Islands, India and identified as Streptomyces sp. VITAK1. The petroleum ether (PE) extract prepared from the culture supernatant of the isolate was purified(More)