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BACKGROUND Studies have shown that metabolic syndrome and its consequent biochemical derangements in the various phases of diabetes may contribute to carcinogenesis. A part of this carcinogenic effect could be attributed to hyperinsulinism. High levels of insulin decrease the production of IGF-1 binding proteins and hence increase levels of free IGF-1. It(More)
BACKGROUND Osteoid osteoma is a benign bone neoplasm which is seen in the long bones of appendicular skeleton. It is rarely seen in the cranium. Skull base osteoid osteoma is extremely rare and has been anecdotally reported. CASE PRESENTATION The authors report a case of a large osteoid osteoma of the ethmoid with intraorbital and intracranial extension(More)
BACKGROUND Giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. The petrous portion of the temporal bone forms a rare location for this tumor. CASE PRESENTATION The authors report a case of a large giant cell tumor involving the petrous and squamous portions of the temporal bone in a 26 year old male(More)
  • K Harish
  • 2005
Background: Neck dissection is an important surgical procedure for the management of metastatic nodal disease in the neck. The gold standard of neck nodal management has been the radical neck dissection. Any modification in the neck dissection is always compared with this standard. Over the last few decades, in order to alleviate the morbidity of radical(More)
BACKGROUND Adenoid cystic carcinoma is a rare malignant parotid tumor. Metastasis can occur even a decade or more after initial treatment of the primary. CASE PRESENTATION We report a 60 year old female patient who presented with adenoid cystic carcinoma of the parotid gland. She underwent a total conservative parotidectomy followed by adjuvant(More)
Several metagenomic projects have been accomplished or are in progress. However, in most cases, it is not feasible to generate complete genomic assemblies of species from the metagenomic sequencing of a complex environment. Only a few studies have reported the reconstruction of bacterial genomes from complex metagenomes. In this work, Binning-Assembly(More)
Background: Locally advanced colorectal cancers form a distinct subgroup where contiguous organs could be involved without distant metastases and so may be amenable to curative surgical resection. It was our objective to report our experience in treating six such patients with operable locally advanced colorectal carcinomas.
BACKGROUND Low grade fibromyxoid sarcomas (LGFMS) are very rarely seen. They commonly arise from deep soft tissues of the lower extremities. Very few cases of intra-abdominal location have been reported. CASE PRESENTATION We report a 37 year old man who presented with an abdominal mass and dragging pain. Pre-operative imaging suggested the possibility of(More)
  • K Harish
  • 2008
INTRODUCTION Well differentiated thyroid carcinoma with isolated involvement of skin is extremely rare. Presentation with a discharging sinus has not been reported. CASE PRESENTATION This is a report of a 62 year old male patient with a long standing history of thyroid swelling which has metastasized to neck nodes and ulcerated over the midline resulting(More)