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Intramolecular isotope effects associated with the benzylic hydroxylation of a series of selectively deuterated isomeric xylenes and 4,4'-dimethylbiphenyl as catalyzed by various rat liver microsomal(More)
The stereochemical course of cytochromes P450 [P4501A1, P4502B1, P4502B4, and P450101 (P450cam)] catalyzed alpha-carbon oxidations of the cis-(Z)- and trans-(E)-5'-d1 diastereomers of (S)-nicotine(More)
Carbocyclic 2',3'-didehydo-2',3'-dideoxy-guanosine [(-)-CBV] is a potent and selective inhibitor of the human immunodeficiency virus. The formation of the (-)-CBV-5'-O-glucuronide has been reported(More)