Kouji Takeya

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Relationship between chemical structure, positive inotropic potency and lethal dose of grayanotoxins and the related compounds was studied using guinea pigs. The positive inotropic effect (PIE) was examined in their papillary muscle isolated from the heart.The potency of these compounds was expressed by pD2 values, and was determined by depicting the(More)
In order to study the function of the gallbladder of diabetic patients, X-ray examination was carried out on 22 normal subjects and 97 diabetic patients concerning the contraction rate of gall-bladder 30 min. and 120min. after yolk-taking. The Predonine-Glucose Tolerance Test was performed on 83 other cholecystitic patients. Following results were obtained.(More)
The inhibition of bacterial growth in thawed cake kept under refrigeration and rapid evaluation methods for microbiological quality of the cake were investigated. The effects of the freezing temperature and the addition of ethanol or emulsifier on bacterial numbers in a cake model after storage for 72 hr at 10 degrees C following the thawing process were(More)
Panax quinquefolium saponin (PQS) increases the contractibility of papillary muscle of guinea pigs during electrical stimulation with frequency of 1/8-1/64Hz (P < 0.05). In Krebs-Henseleit solution purged with gas containing 95% N2 and 5% CO2 regardless of containing glucose or not, PQS (0.3mg/kg) has the effect of anti-hypoxia and anti-glucose deficiency(More)
619 out-patients of the esophageal cancer have visited to our clinic for past 3 years. In these 278 have been resected. In 297 cases who have been carried out resection (malignant 278, benign 19), 180 have been reconstructed by the esophagogastrostomy or the esophagojejunostomy. In the recent 3 years, 1346 cases have been examined by esophagoscopy in our(More)
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