Kou-ichi Tachibana

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We investigated the relationship between intracoronary stenosis detected by multislice computed tomography and various clinical parameters in type 2 diabetic patients with hypertension treated with candesartan (n=42). The results showed that carotid intima-media thickness, but not visceral fat area or adiponectin, correlated significantly with intracoronary(More)
I. Pharmacokinetics (1) CXM 24.4 and 31.9 mg/kg were administered by intravenous drip infusion for 4 hours. The plateau levels were obtained at 1 approximately 2 hours, the blood levels at which time were 25.6 and 33.8 micrograms/ml respectively with dose response observed. (2) The respective half-lives were as short as 49.4 and 36.2 minutes. (3) The total(More)
Twenty-five patients in hospital mainly with lower respiratory tract infections and urinary tract infections were treated with cefotetan (CTT). The drug was given intravenously in a dose of 20 mg per kg body weight 1 to 3 times per day. The response to treatment was satisfactory in the 21 patients (84%). There was slight changes in liver function tests in 2(More)
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