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For quantitative measurements of small animals such as mice or rats, a compact and high sensitivity continuous blood sampling detector is required because their blood sampling volume is limited. For this purpose we have developed and tested a new positron detector. The positron detector uses a pair of dual-layer thin gadolinium orthosilicate (GSO)(More)
Positron emission tomography (PET) with [(11)C]raclopride is widely used to investigate temporal changes in the dopamine D(2) receptor system attributed to the dopamine release. The simplified reference tissue model (SRTM) can be used to determine the binding potential (BP(ND)) value using the time-activity curve (TAC) of the reference region as input(More)
PURPOSE To support preoperative planning of bone drilling for Microendoscopic Discectomy, we present a set of interactive bone-drilling methods using a general 2D pointing device. METHODS Unlike the existing methods, our framework has the following features: (1) the user can directly cut away arbitrary 3D regions on the volumetrically rendered image, (2)(More)
This paper introduces a new design to allow interactive, direct manipulation of volume data on volumetrically rendered images. We present an adaptive volume proxy mesh which serves not to define surfaces, but to encode the geometry and physical state of the volume. This system performs a modeling-free form of direct volume deformation by adaptively(More)
For radio-guided surgery on tumors using F-18-FDG, detection of annihilation gamma photons emanating from other parts of the body produces background radiation counts and limits its use in clinical situations. To overcome this limitation, we have developed an intra-operative positron probe with background-rejection capability. The positron probe uses a(More)
PURPOSE Patient-specific surgical simulation imposes both practical and technical challenges. We propose a segmentation-free, modeling-free framework that creates medical volumetric models for intuitive volume deformation and manipulation in patient-specific surgical simulation. METHODS The proposed framework creates a volumetric model based upon a new(More)
This paper presents a new set of techniques by which surgeons can interactively manipulate patient-specific volumetric models for sharing surgical process. To handle physical interaction between the surgical tools and organs, we propose a simple surface-constraint-based manipulation algorithm to consistently simulate common surgical manipulations such as(More)
Magnetic resonance elastography (MRE) is a method that can visualize the propagating and standing shear waves in an object being measured. The quantitative value of a shear modulus can be calculated by estimating the local shear wavelength. Low-frequency mechanical motion must be used for soft, tissue-like objects because a propagating shear wave rapidly(More)
Tractography is a procedure that can track and demonstrate the 3D neural tracts of the white matter of the brain. The images of the brain are obtained by analyzing the diffusion tensor, identification of which can provide the anatomical connections of the brain. Studying these connections is integral to the understanding of the brain function. Specifically,(More)